The SIGMA Consortium (SIGMA)

The SIGMA Consortium is a hub for the design, contracting, execution, delivery and interpretation of European pharmacoepidemiologic and real-world evidence (PE/RWE) studies, providing a one-stop shop for entities that require research services. The SIGMA Consortium’s VISION is to provide best evidence on the use, benefits and harms of medications, vaccines and devices for the betterment of public health and patient care. Its MISSION is to provide trusted PE/RWE research through a European federated professional network of excellence based on the ENCePP Code of Conduct. The SIGMA Office, co-led by staff from RTI-HS and PHARMO Institute, runs the day-to-day activities of the Consortium for research requests. Each request is distributed to all SIGMA members, who express interest and availability to participate in the study in the role(s) of Coordinating Centre, Principal Investigator Centre and/or Research Site. Study funders can contact the SIGMA Office at info@sigmaconsortium.eu.