Search | HMA-EMA Catalogues of real-world data sources and studies

Results(4953)

Cardiovascular and renal outcomes, and mortality in Danish patients with type 2 diabetes who initiate empagliflozin versus GLP1-RA: A Danish nationwide comparative effectiveness study (EMPLACE)

Denmark

EU PAS number:

EUPAS29985

First published:

04/06/2019

Last updated 05/10/2026

Study Finalised

A regulatory required non interventional study to monitor the safety and effectiveness of once daily treatment of orally inhaled Vahelva Respimat (Tiotropium + Olodaterol fixed dose combination 2.5µg/2.5µg per puff (2 puffs comprise one medicinal dose)) for Korean patients with COPD (Chronic Obstructive Pulmonary Disease) (Vahelva Respimat regulatory Post-marketing Surveil)

Korea, Republic of

EU PAS number:

EUPAS14956

First published:

29/08/2016

Last updated 05/10/2026

Study Finalised

START: Real-world study on sequential therapy with afatinib as first-line treatment in patients with epidermal growth factor receptor (EGFR) mutation-positive advanced non-small cell lung cancer (NSCLC)

China

EU PAS number:

EUPAS32423

First published:

21/11/2019

Last updated 05/10/2026

Study Finalised

Assessment of Real-World Outcomes Associated with Afatinib (Gilotrif) Use in Patients with Solid Tumors Harboring NRG1 Gene Fusions (Afatinib (Gilotrif) Use in Solid Tumors Harboring)

United States

EU PAS number:

EUPAS43164

First published:

23/09/2021

Last updated 05/10/2026

Study Finalised

Non-Interventional Collecting Evidences For ILD in Taiwan: Optimized Novel Therapy (NICEFIT ON)

Taiwan

EU PAS number:

EUPAS37649

First published:

23/10/2020

Last updated 05/10/2026

Study Finalised

Safe Implementation of Treatments in Stroke (SITS) - Intravenous thrombolysis in acute ischaemic stroke patients over 80 years, SITS-IVT>80 years study (SITS ELDERLY)

Austria

Belgium

Cyprus

Denmark

Finland

France

Germany

Greece

Iceland

Ireland

Italy

Luxembourg

Malta

Netherlands

Norway

Portugal

Spain

Sweden

United Kingdom

EU PAS number:

EUPAS33011

First published:

08/02/2020

Last updated 05/10/2026

Study Finalised

Active surveillance research program for the assessment of the safety and the effectiveness of linagliptin

United States

EU PAS number:

EUPAS5790

First published:

29/07/2014

Last updated 05/10/2026

Study Finalised

A retrospective cohort study with chart review to assess the management of major bleeding events in NVAF patients treated with dabigatran etexilate

United States

EU PAS number:

EUPAS6568

First published:

19/05/2014

Last updated 05/10/2026

Study Finalised

Evaluation of the Effectiveness of Implementation of Additional Risk Minimization Measures (aRMM) Materials for Xeljanz® (Tofacitinib) / Rheumatoid Arthritis (RA) indication in Nigeria via a Survey among Prescribers: A Non-Interventional Post Authorization Safety Study (PASS).

Nigeria

EU PAS number:

EUPAS1000000900

First published:

27/05/2026

Last updated 05/10/2026

Study Ongoing

209452 - A targeted safety study, EPI-ZOSTER-030 VS US DB, to evaluate the safety of Shingrix in adults ≥ 50 years of age in the United States

United States

EU PAS number:

EUPAS37156

First published:

11/09/2020

Last updated 05/10/2026

Study Finalised

A multicentre international randomized parallel group double-blind placebo-controlled clinical trial of EMPAgliflozin once daily to assess cardio-renal outcomes in patients with chronic KIDNEY disease (EMPA-KIDNEY)

Canada

China

Germany

Italy

Japan

Malaysia

United Kingdom

United States

EU PAS number:

EUPAS46175

First published:

11/03/2022

Last updated 05/10/2026

Study Finalised

DOLOMITE NEAT ID Network Study: A prospective, multi-site observational study to define the safety and effectiveness of Dolutegravir use in HIV positive pregnant women (208759)

Belgium

France

Italy

Poland

Portugal

Spain

Ukraine

United Kingdom

EU PAS number:

EUPAS24237

First published:

30/05/2018

Last updated 05/10/2026

Study Ongoing

Universitätsklinikum Frankfurt (UKF)

Germany

First published:

05/10/2026

Last updated 05/10/2026

Institution Hospital/Clinic/Other health care facility

Use of antipsychotics in children and adolescents in the Spanish National Health System: network project with real-world data from five Autonomous Communities to inform evidence-based health policies (Children and Adolescents Antipsychotic Research for Evidence-based Strategies – CARES Project)

Spain

EU PAS number:

EUPAS1000000591

First published:

11/09/2026

Last updated 02/10/2026

Study Ongoing

An Observational Study to Describe the Long-term Safety and Effectiveness of Namuscla in the Symptomatic Management of Myotonia in Adult Patients with Non-dystrophic Myotonic Disorders

France

Germany

United Kingdom

EU PAS number:

EUPAS37943

First published:

10/11/2020

Last updated 02/10/2026

Study Finalised

The Comparative Safety and Effectiveness of Warfarin and Dabigatran Utilized in the Department of Defense (DoD) Non-Valvular Atrial Fibrillation (NVAF) Patient Population-A Retrospective Database Analysis

United States

EU PAS number:

EUPAS9771

First published:

20/05/2015

Last updated 02/10/2026

Study Finalised

The effectiveness of Tiotropium Add-on therapy using a Real-world cohort of patients with Asthma (Tiotropium therapy in Asthma)

United States

EU PAS number:

EUPAS29889

First published:

29/05/2019

Last updated 02/10/2026

Study Finalised

DARWIN EU® - A RWD study to evaluate drug utilisation of Long-acting Insulin analogues and Neutral Protamine Hagedorn Insulin in clinical practice

Croatia

Denmark

France

Germany

Lithuania

Spain

Sweden

United Kingdom

EU PAS number:

EUPAS1000001135

First published:

02/10/2026

Last updated 02/10/2026

Study Ongoing

DARWIN EU® - Sex differences in treatment patterns for venous thromboembolic events in European countries

Denmark

Finland

Netherlands

Spain

United Kingdom

EU PAS number:

EUPAS1000001079

First published:

06/08/2026

Last updated 02/10/2026

Study Ongoing

Validation of predictors for oral anticoagulant medication choice using EMR data

United States

EU PAS number:

EUPAS16314

First published:

03/01/2017

Last updated 01/10/2026

Study Finalised

Safety of dabigatran etexilate (DE) for treatment of venous thromboembolism (VTE) and prevention of recurrent VTE in paediatric patients from birth to less than 2 years of age: a prospective European non-interventional cohort study based on new data collection (1160.307)

Austria

Czechia

Denmark

Finland

Germany

Italy

Netherlands

Spain

Sweden

EU PAS number:

EUPAS47909

First published:

29/06/2022

Last updated 01/10/2026

Study Finalised

Real-World Effectiveness of COVID-19 Vaccines in the Netherlands: Causal Inference From A Retrospective Cohort Study Using the Target Trial Emulation framework Within the PharmLines Initiative

Netherlands

EU PAS number:

EUPAS1000000785

First published:

01/10/2026

Last updated 01/10/2026

Study Ongoing

VIMKUNYA® Pregnancy registry: An Observational Prospective Study of the Safety of VIMKUNYA® Vaccine Exposure in Pregnant Women and their Offspring

Germany

United Kingdom

United States

EU PAS number:

EUPAS1000001126

First published:

01/10/2026

Last updated 01/10/2026

Study Ongoing

Effectiveness of Adjuvanted Recombinant Zoster Vaccine (RZV) Against Postherpetic Neuralgia (PHN) and Against Cardiovascular Disease (CVD) Events After Herpes Zoster (HZ) in United States Adults in Medicare Fee-for-Service (FFS) + Inovalon’s MORE2 Registry (307298 - EPI-ZOSTER-116 VE DB US)

United States

EU PAS number:

EUPAS1000001125

First published:

01/10/2026

Last updated 01/10/2026

Study Planned

Real-world clinical outcomes, patient characteristics, and treatment patterns among patients with locally advanced unresectable or metastatic human epidermal growth factor receptor 2-negative, claudin-18 isoform 2-positive gastric or gastroesophageal junction adenocarcinoma treated with zolbetuximab or other first line treatments: A cohort study using secondary data in Europe and Canada (RADIANCE)

Canada

France

Germany

Portugal

Spain

Sweden

EU PAS number:

EUPAS1000001120

First published:

01/10/2026

Last updated 01/10/2026

Study Ongoing

Evaluating Safety in Insulin-Requiring Diabetic Patients Receiving Inavolisib Plus Endocrine Therapy-Based Regimens in the Real World

United States

EU PAS number:

EUPAS1000001124

First published:

01/10/2026

Last updated 01/10/2026

Study Planned

Non-interventional study of patients with Netherton Syndrome to characterise the natural history of disease (Natural history of Netherton Syndrome)

Austria

China

France

Germany

Italy

Japan

Netherlands

United Kingdom

United States

EU PAS number:

EUPAS103733

First published:

27/02/2023

Last updated 01/10/2026

Study Discontinued

Assessment of physical functioning and handling of Spiolto Respimat in patients with chronic obstructive pulmonary disease (COPD) requiring long-acting dual bronchodilation in routine clinical practice (OTIVACTO)

Belgium

Denmark

Luxembourg

Netherlands

Portugal

Sweden

EU PAS number:

EUPAS12750

First published:

18/03/2016

Last updated 01/10/2026

Study Finalised

A multicentre, retrospective chart review study to describe the clinical profile of idiopathic pulmonary fibrosis (IPF) patients treated with nintedanib (OFEV®) in real-world practice in Spain (BROAD)

Spain

EU PAS number:

EUPAS19384

First published:

01/06/2017

Last updated 01/10/2026

Study Finalised

A regulatory non-interventional study to monitor the safety and efficacy of JARDIANCE® (Empagliflozin 10 mg) in Korean patients with Chronic Kidney Disease (CKD)

Korea, Republic of

EU PAS number:

EUPAS107293

First published:

24/10/2023

Last updated 01/10/2026

Study Finalised

Non-interventional, cross-sectional, multicenter study to describe the exacerbations profile of COPD patients Treated with ICS in a real-life primary care population in Spain. OPTI Study

Spain

EU PAS number:

EUPAS22940

First published:

05/03/2018

Last updated 01/10/2026

Study Finalised

D-SOLVE Clinical Cohorts

Germany

Italy

Romania

Sweden

First published:

24/03/2025

Last updated 01/10/2026

Data source

Human

Biobank Disease registry Hospital outpatient visit records

Record completeness: 70%

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Cooperative European Paediatric Transplant Initiative Liver

Argentina

Canada

China

France

Germany

India

Italy

Poland

Portugal

Singapore

Spain

Switzerland

Türkiye

United Kingdom

United States

First published:

29/09/2025

Last updated 01/10/2026

Data source

Human

Disease registry

Record completeness: 76%

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Cooperative European Paediatric Renal Transplant Initiative

Austria

Belgium

Bulgaria

Croatia

Czechia

France

Germany

Greece

Hungary

Ireland

Israel

Italy

Netherlands

Poland

Portugal

Romania

Serbia

Slovenia

Spain

Switzerland

Türkiye

United Kingdom

First published:

08/10/2025

Last updated 01/10/2026

Data source

Human

Disease registry

Record completeness: 78%

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Danny Platform

Bulgaria

Croatia

Poland

Romania

Serbia

Slovenia

Spain

First published:

01/02/2024

Last updated 01/10/2026

Data source

Human

Death registry Drug registry Hospital inpatient records Other Pharmacy dispensing records Primary care medical records

Record completeness: 90%

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Vetcompendium

Belgium

First published:

01/10/2026

Last updated 01/10/2026

Data source

Veterinary

Website

Record completeness: 93%

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Veterinary Companion Animal Surveillance System

United Kingdom

First published:

01/10/2026

Last updated 01/10/2026

Data source

Veterinary

Website

Record completeness: 81%

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Animal Health Data Service-AHDS

Austria

First published:

01/10/2026

Last updated 01/10/2026

Data source

Veterinary

Tooling

Record completeness: 100%

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Dyreforsøgstilsynet (The Animal Experiments Inspectorate)

Denmark

First published:

01/10/2026

Last updated 01/10/2026

Data source

Veterinary

Website

Record completeness: 93%

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Antimicrobial resistance monitoring results complementing the European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2022/2023 – Croatia

Croatia

First published:

01/10/2026

Last updated 01/10/2026

Data source

Veterinary

Raw data

Record completeness: 93%

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Results(4953)