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Isha Naz
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Publications
Data source publications
- Approach to record linkage of primary care data from Clinical Practice Research Datalink to other health-related patient data: overview and implications
- Data Resource Profile: Clinical Practice Research Datalink (CPRD)
- Data resource profile: Clinical Practice Research Datalink (CPRD) Aurum
- Utilisation and Safety of Polyethylene Glycol 3350 With Electrolytes in Children Under 2 Years: A Retrospective Cohort
Studies
List of studies that have been conducted using the data source
- EUROmediCAT: Safety of Medication Use in Pregnancy in Relation to Risk of Congenital Malformations
- Exposure to beta-blockers and survival in breast cancer patients: A cohort study using the UK General Practice Research Database.
- Calcium channel blocker treatments and cancer risk. A methodological protocol to compare the results between databases, across designs: Evaluation of the impact of design/database/population differences on the outcome of the studied association
- Isotretinoin and the effectiveness of the pregnancy prevention programmes in Europe
- WP6 Replication Study: The risk of acute liver injury associated with the use of antibiotics: Population based case control study
- A/H1N1 pandemic vaccines and pregnancy outcomes
- Use of benzodiazepines and risk of hip/femur fracture. A methodological comparison across data sources and epidemiological design.
- Use of inhaled long acting beta2 adrenoceptor agonists and the risk for Acute Myocardial Infarction (AMI). A methodological comparison across data sources and epidemiological design
- Asthma treatment in pregnancy and the frequency of adverse pregnancy outcomes (WEUSRTP4850)
- Metabolic effects associated with ICS (inhaled corticosteroid) use in COPD (chronic obstructive pulmonary disease) patients with type II diabetes
- Increasing ICS Dose vs Add-on Therapy in Children with Asthma (Paediatric Asthma Step-up)
- CAncer Risk and INsulin analoGues (CARING) project
- Strattera patient exposures and adherence in the United Kingdom, Germany, the Netherlands, and Sweden: 2016 Bi-annual assessment report. (B4Z-MC-B025)
- Burden of severe uncontrolled eosinophilic asthma in the UK population
- Use of antiepileptics and risk of suicidality. An exploratory study using the UK General Practice Research Database (GPRD) and data from the Danish registries with an evaluation of available data from further European data sources.
- The Association between Long-Acting Beta-Agonists and Prescribing of Oral Steroids for Asthma Exacerbations
- A study on the utilization of pioglitazone in clinical practice in the UK after the label change in July 2011
- A Study on the Utilization of Pioglitazone in Clinical Practice With Regard to Diabetic Treatment Regimen and Comorbidities
- Monitoring for proteinuria in patients with type 2 diabetes mellitus (Proteinuria monitoring in type 2 diabetes)
- Benefits of high dose ICS in patients with asthma and high blood eosinophil counts
- Characteristics and Treatment Patterns of Patients with Chronic Obstructive Pulmonary Disease (COPD), Initiating Tio+Olo or Other Maintenance Therapies in the US and the UK: A Retrospective Claims Database Study.
- Use of Nalmefene (Selincro®) in European databases: Cohort design using longitudinal electronic medical records or claims databases
- Burden of disease in patients with COPD and high blood eosinophil counts (High eosinophils and COPD)
- A multi-database cohort study to assess the incidence rates of colorectal hyperplasia among hypertensive patients
- Prevalence and Incidence of Problematic Prescription Opioid Use and Abuse in the United Kingdom and Germany (OXY9504)
- Intended and unintended effects of Z-drug use for sleep disturbance in people with dementia – ‘Z-drug Evaluation in Dementia’ (ZED)
- Usage Patterns of Selected Systemic NSAIDs (Including Diclofenac): A Retrospective Cohort Study
- A Postmarketing Observational Evaluation of the Safety of FLUENZ in Children and Adolescents With High-risk Conditions
- Risk of lactic acidosis with metformin use in type 2 diabetes mellitus with renal impairment: retrospective cohort study
- A Nested Case-control Post-authorization Safety Study of Etoricoxib and Other Non-steroidal Anti-inflammatory Therapies in a Cohort of Patients with Ankylosing Spondylitis (AS) in the UK, France and Germany (MK-0663-163)
- Incidence of Thyroid Neoplasm and Pancreatic Cancer in Type 2 Diabetes Mellitus Patients who Initiate Once Weekly Exenatide Compared with Other Antihyperglycemic Drugs
- Effectiveness of triple therapy vs. dual bronchodilation in COPD (Effectiveness of triple therapy in COPD)
- Combined bronchodilators in COPD and the risk of adverse cardio-pulmonary events: A population-based observational study (Comb Bronchodil in COPD and CardPulm AEs)
- Pan European Multi-Database Bladder Cancer Risk Characterisation Study
- Decline In lung-function Among Patients with chronic obstructive Lung disease On maintenance therapy (DIAPLO)
- Association between anxiolytic or hypnotic drugs and total mortality
- Prasugrel Treatment Patterns in Outpatient Settings in Germany, the United Kingdom, and France (H7T-MC-B011)
- Strattera patient exposures and adherence in the United Kingdom, Germany, the Netherlands, and Sweden: 2014 Bi-annual assessment report
- Safety Evaluation of Adverse Reactions in Diabetes - Drug utilisation studies (SAFEGUARD)
- Safety Evaluation of Adverse Reactions in Diabetes - Comparative studies (SAFEGUARD)
- Characteristics of patients initiating empagliflozin or other non-insulin glucose lowering drugs in the United Kingdom (Empa DUS in UK)
- Stress Urinary Incontinence and Suicidality Seen in the United Kingdom General Practice Research Database (F1J-MC-B056)
- A Drug Utilisation Study of Domperidone in Europe Using Databases
- Incidence and pattern description of gastrointestinal, skin, genital, corneal, and mucosal erosions, ulcerations, perforations, haemorrhages, fistulas, abscesses, delayed wound healing and death among patients treated with nicorandil with and without diverticular disease
- Longitudinal Analyses of Body Mass Index and Risk of Parkinson's Disease in 2 million people over 2 decades (BMI and Parkinson´s disease)
- Longitudinal Analyses of Blood Pressure and Risk of Alzheimer´s disease and Vascular Dementia in 2.6 million people over 2 decades (BP and Dementia)
- Multinational Observational Database Study on Imminent Osteoporotic Fracture Risk: Stage 1 (IFRISK)
- Post-authorisation Safety Study: Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Users of Proton Pump Inhibitors, and Users of Metoclopramide
- An Observational Drug Utilization Study of SYCREST® (asenapine) in the United Kingdom (P08308)
- An Observational Post-Authorization Safety Surveillance (PASS) Study of SYCREST® (asenapine) among Patients aged 18 and older Diagnosed with Bipolar Disorder (P08307)
- Asthma and Type 2 Comorbidities - Real-life Characterisation of Patients with Active Asthma and Type 2 Asthma Comorbidities
- The use of a spacer in the delivery of large (Fluticasone Propionate) and small particle (Qvar®) inhaled corticosteroid (ICS) in asthma (FP and Qvar Spacer vs Non-Spacer in Asthma)
- Persistence and compliance to anti-osteoporosis medications in the United Kingdom using the Clinical Practice Research Datalink (CPRD) (20160192)
- Evaluation of potential off-label use of dabigatran etexilate in Europe
- Utilisation of antiepileptic medicines in girls and women of childbearing potential - a study in three European countries
- Investigating the possible role of BLood eosinophil counts in guiding ANti-inflammatory treatment of COPD exAcerbations (BLANCA)
- Real-world effectiveness of extra-fine formulations in Denmark
- Benzodiazepine and anticholinergic use and incident dementia (ABCD study)
- Evaluation of the undertreatment and disease outcomes for patients with coexisting Heart Failure and Chronic Obstructive Pulmonary Disease
- An observational historical cohort study to evaluate chronic disease onset associated with long-term oral corticosteroid and it’s cost impact on patients in the OPCRD / CPRD databases
- Dose response curves for patients prescribed small & large particle ICS formulation: an observational evaluation of the comparative effect of ICS dose on asthma control achieved in real-life UK patients managed on extrafine hydrofluoroalkane beclomethasone, ciclesonide, fluticasone propionate, or Clenil
- Historical matched-cohort study assessing whether the use of inhaled corticosteroids shortens time to first diagnosis or accelerates the progression of side effects compared to non-ICS therapies in patients with Chronic Obstructive Pulmonary Disease. (ICS use in COPD patients and risk of side effects)
- A non-interventional study of LAIV utilization to identify and characterize medication errors due to expired vaccine use in individuals 2-17 years of age in the CPRD
- Risks and benefits of bisphosphonate use in patients with chronic kidney disease: a population-based cohort study
- A RETROSPECTIVE, REAL-LIFE EVALUATION OF THE CARDIOVASCULAR DISEASE RISK ASSOCIATED WITH EXPOSURE TO PHARMACOLOGICAL SMOKING CESSATION INTERVENTIONS IN A REPRESENTATIVE UK PRIMARY CARE PATIENT POPULATION
- Comparative effectiveness of combination therapies in COPD
- A drug utilisation study of Rifaxamin-α 550mg
- Comparative effectiveness of triple therapy in COPD: A new-user cohort study
- The risk of acute liver injury associated with the use of antibiotics. A methodological comparison across epidemiological data sources
- Strattera patient exposures and adherence in the United Kingdom, Germany, the Netherlands, and Sweden: 2018 Bi-annual assessment report (B4Z-MC-B026)
- Drug utilization study of mirabegron (Betmiga®) using real-world healthcare databases from the Netherlands, Spain, United Kingdom and Finland (Mirabegron DUS)
- Association between the Prevalence of cardiovascular risk factors and new use of testosterone
- Health outcomes of patients with acute coronary syndromes prescribed ticagrelor in UK primary care: a retrospective cohort study (Outcomes in UK ACS patients prescribed ticagrelor)
- Excess risk and predictors of fracture/s following bariatric surgery for obese patients in the NHS: a real-world self-controlled case series and cohort study
- A prediction model for future exacerbation risk in children
- Eosinophilic asthma phenotypes and associated clinical outcomes
- 205639 - Meta-analysis of the risk of autoimmune thyroiditis diseases, Guillain-Barré Syndrome, and Inflammatory Bowel Disease with Cervarix Vaccination
- An observational evaluation of prescribing of fixed-dose combination inhaled corticosteroid / long-acting beta2-agonist (ICS/LABA): fluticasone propionate / formoterol (FP/FOR) and adverse events in routine primary care at 18-months and 36-months post launch
- Comparative Assessment of VTE and Other Risks among Patients with Rheumatoid Arthritis treated with Baricitinib versus Tumor Necrosis Factor Inhibitors: A Multi-database Observational Cohort Study
- Post-authorization Safety Study Evaluation of Neoplasm Events in Users of Mirabegron and Other Treatments for Overactive Bladder : Core Common Protocol
- The Impact of Exacerbation Burden on Lung Function Trajectory in a Broad Asthma Population and Severe Asthma Population (Exacerbation and lung function trajectory)
- A Joint Drug Utilisation Study (DUS) of valproate and related substances, in Europe, using databases
- Risk of angiotensin converting enzyme inhibitor intolerance in asthma compared to the general population
- Impact of EU label changes for systemic diclofenac products: post-referral prescribing trends
- Ability of primary care health databases to assess medicinal products discussed by the European Union Pharmacovigilance Risk Assessment Committee (CAPs and NAPs in primary EHDs)
- Linaclotide Utilisation Study in Selected European Populations
- Bendroflumethiazide versus Indapamide for Primary Hypertension: Observational (BISON) study within CPRD
- Risk of switching to angiotensin-II receptor blocker therapy in people with asthma who initiate ACE inhibitor therapy compared to the general population: a retrospective cohort study
- Pattern of use of Direct Oral Anticoagulants in Non-valvular Atrial Fibrillation patients in UK general practices
- Post-authorization Safety Study Evaluation of Cardiovascular Events in Users of Mirabegron and Other Treatments for Overactive Bladder
- Pharmacological risk factors for COVID-19 infection: a matched prospective cohort study of patients in primary care
- NN304-4528: Retrospective Cohort study of all-Cause and Cardiovascular Mortality in type 2 diabetes patients using basal insulin Detemir and Glargine
- Hydroxychloroquine safety and potential efficacy as an antiviral prophylaxis in light of potential wide-spread use in COVID-19: a multinational, large-scale network cohort and self-controlled case series study
- Diagnosis and management of infectious disease in primary care during the COVID-19 lockdown: changes in antibacterial and antiviral use
- A Retrospective Cohort Study to Assess Drug Utilisation and Long-Term Safety of Galcanezumab in European Patients in the Course of Routine Clinical Care (I5Q-MC-B002)
- An Observational Study of the Risk of Malignant Neoplasms and Malignant Neoplasms of Special Interest (Thyroid and Pancreatic Cancer) in Subjects Treated with Albiglutide Compared to Those Treated with Other Antidiabetic Agents (201805)
- European non-interventional post-authorization safety study related to serious cardiovascular events of myocardial infarction and stroke, and all-cause mortality for romosozumab by the EU-ADR Alliance
- EUROPEAN NON-INTERVENTIONAL POST-AUTHORIZATION SAFETY STUDY RELATED TO ADHERENCE TO THE RISK MINIMIZATION MEASURES FOR ROMOSOZUMAB BY THE EU-ADR ALLIANCE
- EUROPEAN NON-INTERVENTIONAL POST AUTHORIZATION SAFETY STUDY RELATED TO SERIOUS INFECTIONS FOR ROMOSOZUMAB BY THE EU ADR ALLIANCE
- Utilisation of dulaglutide in European countries: A cross-sectional, multi-country and multi-source drug utilisation study using electronic health record databases (H9X-MC-B010)
- An Observational/Non-interventional Evaluation of Subject Outcomes for Type 2 Diabetes Mellitus (T2DM) Subjects Prescribed Dipeptidyl Peptidase-4 Inhibitors (DPP4i), Sodium-glucose Cotransporter-2 Inhibitors (SGLT2i) or Sulphonylureas (SUs) at First Intensification
- Impact of EU label changes for hydroxyzine products: post-referral prescribing trends
- Post-Authorization Safety Program—Validation of the Clinical Practice Research Datalink for the Study of Cardiovascular and Neoplasm Events in Users of Treatments for Overactive Bladder
- A longitudinal study of 4 cohorts of patients with psoriasis and psoriatic arthritis: one treated with Otezla (apremilast), one with an injectable comparator drug, one with an oral comparator drug and one with an oral and an injectable comparator drug (Otezla-CPRD-001)
- Aclidinium Bromide Drug Utilisation Post-Authorisation Safety Studies (DUS): Common Protocol for Aclidinium (DUS1) and Aclidinium/Formoterol Fixed-Dose Combination (DUS2)
- Project Sc(y)lla: SARS-Cov-2 Large-scale Longitudinal Analyses on the comparative safety and effectiveness of treatments under evaluation for COVID-19 across an international observational data network
- Utilisation of oral anticoagulants in older people with atrial fibrillation in UK general practice
- The risk of musculoskeletal adverse outcomes after treatment with endocrine blocking treatments for breast cancer (MSKAI)
- A comparison of the effectiveness and safety of direct oral anticoagulants versus warfarin in older patients with atrial fibrillation using the Clinical Practice Research Datalink
- Linaclotide Safety Study for the Assessment of Diarrhoea—Complications and Associated Risk Factors in Selected European Populations with IBS-C
- Post-marketing study of ropinirole prolonged release tablets in Parkinson’s disease: Evaluation outcomes associated with long term use of Ropinirole-PR using the clinical practice research datalink (CPRD) (111981)
- Longitudinal Analyses of Blood Lipids and Future Risk of Dementia in CPRD (Lipids and dementia)
- Impact of risk minimisation in patients treated with rosiglitazone-containing products
- Metformin use in renal impairment
- Influence of safety advisories on drug utilization: an international interrupted time series study
- Post-authorization safety Electronic Medical Records database retrospective cohort study of new users of inhaled UMEC/VI or new users of inhaled UMEC in the primary care setting
- Pancreatic Cancer and Thyroid Cancer Risks with Dulaglutide Treatment
- WEUSKOP6416: Evaluating severe events in patients with Chronic Obstructive Pulmonary Disease (COPD) to inform risk minimization: A Retrospective Observational Study (116952)
- A cohort study to investigate the prescribing of albiglutide among women of child-bearing age who have type 2 diabetes (201795)
- Aclidinium Bromide Post-Authorisation Safety Study to Evaluate the Risk of Cardiovascular Endpoints
- Drug utilisation studies using data mapped to the OMOP Common Data Model: a proof of concept study assessing respiratory drug use in patients with asthma or COPD
- Cohort Study of the Relative Incidence of Major Cardiovascular Events Among Patients Initiating Prucalopride Versus a Matched Comparator Cohort
- Methods for controlling by indication for prescriptions: application to medications for neuropathic pain
- Demonstrating solutions for studying intermittent medication exposures in diseases with episodic manifestations during pregnancy: application to medication for migraine in pregnancy
- Overactive bladder anticholinergics and risk of incident dementia: a cohort study design using a triangulation approach
- EUMAEUS: Evaluating Use of Methods for Adverse Event Under Surveillance (for vaccines)
- Assessment of off-label use of baricitinib in the paediatric population (Paediatric use of baricitinib)
- Drug utilization study for Elvanse® / Tyvense® / Elvanse® Adult in Europe
- Effectiveness of Indapamide SR on top of Perindopril on blood pressure change: a methodological study to validate effect of anti-hypertensive drugs in CPRD Aurum.
- Natural history of coagulopathy and use of anti-thrombotic agents in COVID-19 patients and persons vaccinated against SARS-CoV-2
- Monitoring safety of Spikevax in pregnancy: an observational study using routinely collected health data in five European countries (COVID-19)
- Post-Authorization Active Surveillance Safety Study Using Secondary Data to Monitor Real-World Safety of Spikevax in Europe (COVID-19)
- Characterising the risk of major bleeding in patients with Non-Valvular Atrial Fibrillation: non-interventional study of patients taking Direct Oral Anticoagulants in the EU
- Risk of Skin Cancer and Lymphoma in Users of Topical Tacrolimus, Pimecrolimus, and Corticosteroids (JOELLE)
- ASSOCIATION BETWEEN THROMBOSIS WITH THROMBOCYTOPENIA SYNDROME (TTS) OR THROMBOEMBOLIC EVENTS, AND COVID-19 VACCINES
- Post Conditional Approval Active Surveillance Study Among Individuals in Europe Receiving the Pfizer-BioNTech Coronavirus Disease 2019 (COVID-19) Vaccine
- An Observational Post-Authorisation Safety Study (PASS) of Patients with Chronic Opioid Use for Non-Cancer Pain and Cancer Pain who have Opioid-Induced Constipation (OIC) (Naldemedine PASS)
- Burden and consequences of the use of COPD-related systemic corticosteroids (OCS COPD study)
- Post-Authorisation Active Surveillance Study of Myocarditis and Pericarditis Among Individuals in Europe Receiving the Pfizer-BioNTech Coronavirus Disease 2019 (COVID-19) Vaccine
- PCSCVM003617/ A Real-World Database Study of Canagliflozin Utilization in Type 1 Diabetes Patients Over Time among European Countries
- An observational cohort study to describe intermittent OCS utilisation and its association with adverse outcomes and healthcare resource use and costs in asthma using the OPCRD and CPRD databases. (The burden of intermittent OCS use in asthma)
- Investigating biases in observational studies of inhaled corticosteroids and the risk of COVID-19-related outcomes
- Utilisation of low-dose rivaroxaban in patients with atherosclerotic cardiovascular disease in the united kingdom and the netherlands
- Drug utilisation study of new users of fluticasone furoate / vilanterol (FF/VI) in the primary care setting: UK Clinical Practice Research Datalink (CPRD) study (205052)
- PRJ2282/201491: CHESS: CPRD-COPD Hawthorne Effect Study in Salford: A UK cohort study to characterise patients enrolled in the Salford Lung Study and to evaluate a potential Hawthorne effect
- Exposure to pioglitazone and the risk of prostate cancer: a nested case-control study
- Post-authorisation safety study to assess the risk of urinary tract malignancies in relation to empagliflozin exposure in patients with type 2 diabetes: a multi-database European study (PASS DiabCancer)
- A post-authorisation/post-marketing observational study to evaluate the association between exposure to AZD1222 and safety concerns using existing secondary health data sources (COVID-19)
- Non-interventional post-authorization multi-database safety study to characterize the risk of angioedema and other specific safety events of interest in association with use of Entresto® (sacubitril/valsartan) in adult patients with heart failure
- Non-Interventional retrospective longitudinal study in the United Kingdom and France to investigate the therapeutic strategies after discontinuation of valproate and related substances in clinical practice (VALSE study - VALNAC09344)
- Observational Studies in Cancer Associated Thrombosis for Rivaroxaban – United Kingdom Cohort (OSCAR—UK)
- A Drug Utilisation Study extension (DUS ext.) of valproate and related substances, in Europe, using databases (VALNAC09343)
- Non-interventional post-authorization multi-database safety study to assess the risk of myotoxicity, hepatotoxicity and acute pancreatitis in statin-exposed heart failure patients with or without concomitant use of sacubitril/valsartan (Entresto®)
- FINErenone druG Utilization Study and assessment of Temporal changes following availability of different treatment options in patients with chronic kidney disease and type 2 diabetes (FINEGUST)
- E2090-E044-501: A Retrospective database Study of the Prescribing of Zonismaide in UK General Practice: A Drug Utilisation Study as Part of Post-Marketing Safety Surveillance
- A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients who Initiated Exenatide as Compared with those who Initiated Other non-Glucagon-Like Peptide 1 Receptor Agonists based Glucose Lowering Drugs (EXCEED)
- Strengthening Use of Real-World Data in Medicines Development: Metadata for Data Discoverability and Study Replicability (MINERVA)
- Comparison of the Risk of Cancer Between Patients With Type 2 Diabetes Exposed to Dapagliflozin and Those Exposed to Other Antidiabetic Treatments
- Concordance between primary and secondary electronic healthcare databases: A multi-database self-controlled case series study
- Hearing loss and risk of major osteoporotic fracture: a population-based cohort study in the United Kingdom (20200418)
- Impact of EU label changes and revised pregnancy prevention programme for medicinal products containing valproate: utilisation and prescribing trends
- Safety of Paxlovid During Pregnancy
- Safety of Paxlovid Among Patients with Moderate or Severe Hepatic or Renal Impairment
- Association between COVID-19 vaccines and paediatric safety outcomes in children and adolescents aged 5-19 years in the Nordic countries: Myocarditis, pericarditis and thromboembolic events
- Effectiveness of heterologous and booster Covid-19 vaccination in 5 European countries, using a cohort approach in children and adults with a full primary Covid-19 vaccination regimen (Covid Vaccines Effectiveness (CoVE))
- NN8022-4246 In market utilisation of liraglutide used for weight management in the UK: a study in the CPRD primary care database
- Reproducible Evidence: Practices to Enhance and Achieve Transparency (REPEAT)
- Cohort monitoring of Adverse Events of Special Interest and COVID-19 diagnoses prior to and after COVID-19 vaccination (ECVM)
- Rapid Safety Assessment of SARS-CoV-2 vaccines in EU Member States using electronic health care datasources (CVM Covid19-Vaccine-Monitor-EHR)
- Background rates of Adverse Events of Special Interest for monitoring COVID-19 vaccines (ACCESS-BGR)
- Comparison of the Risk of Acute Kidney Injury Between Patients With Type 2 Diabetes Exposed to Dapagliflozin and Those Exposed to Other Antidiabetic Treatments
- Comparison of the Risk of Acute Liver Injury Between Patients With Type 2 Diabetes Exposed to Dapagliflozin and Those Exposed to Other Antidiabetic Treatments
- Comparison of the Risk of Severe Complications of Urinary Tract Infections (UTI) Between Patients With Type 2 Diabetes Exposed to Dapagliflozin and Those Exposed to Other Antidiabetic Treatments
- Post-authorisation safety study in patients with type 2 diabetes mellitus to assess the risk of acute liver injury, acute kidney injury and chronic kidney disease, severe complications of urinary tract infection, genital infections, and diabetic ketoacidosis among patients treated with empagliflozin compared to patients treated with DPP-4 inhibitors (PASS renal, liver injury, infection, ketoacidosis)
- Multi-country non-interventional study on the effectiveness and safety of Empagliflozin in adult patients with type 2 diabetes in Europe and Asia
- DARWIN EU® Prevalence of rare blood cancers in Europe
- DARWIN EU® Drug utilisation of valproate-containing medicinal products in women of childbearing potential
- DARWIN EU® DUS of Antibiotics in the ‘Watch’ category of the WHO AWaRe classification of antibiotics for evaluation and monitoring of use
- Safety of the Novavax COVID-19 vaccine in England using a self-controlled case series design: A post-authorisation safety study using data from the Clinical Practice Research Datalink (CPRD) Aurum and linked databases
- DARWIN EU® - Background rates of serious adverse events to contextualise safety assessments in clinical trials and non-interventional studies in adolescent and adult patients with severe asthma
- Association between opioid use and the development of diverticulitis (Opioids Diverticulitis)
- Post-authorisation Safety Study of Rimegepant in Patients with Migraine and History of Cardiovascular Disease in European Countries
- Comparing Database Harmonisation Methods Applied to Real-World Electronic Healthcare Data
- Utilization of antidementia treatments: a large multinational-network population-based study.
- The Impact of COVID-19 Pandemic on Drug Use: Implications for Regulatory Intervention Impact Studies
- mRNA-1273-P910: Clinical course, outcomes and risk factors of myocarditis and pericarditis following administration of Moderna vaccines targeting SARS-CoV-2.
- Comparing the risk of metoprolol-related adverse drug reactions between women and men with heart failure using effectiveness outcomes as a proxy: a population-based cohort study using CPRD
- Characterization of the epidemiology, treatment patterns and burden of Pulmonary Hypertension Group 1 and 3 in France, Germany and the UK: a real-word evidence study (PHILD_RWE_FR_DE_UK)
- Characterization of neurodevelopmental disorders in children exposed in utero to valproate and/or other antiepileptic drugs with long-term follow-up: retrospective study of multiple European data sources (AVALON)
- DARWIN EU® Use of take-home naloxone for opioid overdose treatment
- EHDS2 Pilot Use Case: Natural history of coagulopathy in COVID-19 patients and persons vaccinated against SARS-CoV-2 during the Omicron period.
- Incidence, prevalence, and characterisation of medicines with suggested drug shortages in Europe
- Dipeptidyl Peptidase-4 Inhibitors and Inflammatory Bowel Disease Risk: Impact of Study Design Differences on Comparative Safety Results
- PredictIng the risk for first COPD severe exacerbation (PRECISE-X)
- Post-Authorisation Safety Study of Comirnaty Original/Omicron BA.1 and Comirnaty Original/Omicron BA.4-5 in Europe
- Monitoring the effectiveness of risk minimisation in patients treated with pioglitazone-containing products
- Comparing the Estimated Risk of Hip Fracture Among Subjects Exposed to Tramadol as Compared to Subjects Exposed to Codeine (Tramadol vs Codeine)
- Long-term real-world safety of ozanimod – A post-authorisation safety study (PASS) in patients diagnosed with ulcerative colitis
- Cardiovascular outcomes of treat-to-target vs fire-and-forget urate-lowering therapy in patients with gout starting urate-lowering therapy. An emulated multicentre open-label two-parallel arm superiority trial carried out in primary care
- A Post-Authorisation Safety Study (PASS) of ABRYSVO (Respiratory Syncytial Virus Stabilised Prefusion Subunit Vaccine) in Pregnant Women and their Offspring in a Real World Setting in Europe and UK
- Post-Authorization Safety Study to Assess the Effectiveness of the Newly Implemented Risk Minimization Measures for Topiramate: Drug Utilization Study