The Association between Long-Acting Beta-Agonists and Prescribing of Oral Steroids for Asthma Exacerbations

Study identification

• EU PAS number:
  EUPAS13490
• Study ID:
  14260
• Official title and acronym:
  The Association between Long-Acting Beta-Agonists and Prescribing of Oral Steroids for Asthma Exacerbations
• DARWIN EU® study:
  No
• Study countries:
  United Kingdom
• Study description:
  This cohort study aims to examine the comparative effectiveness of inhaled long-acting beta-agonist (LABA), inhaled corticosteroid (ICS), and ICS/LABA combinations. Patients older than 12 years with asthma diagnosis in the Clinical Practice Research Datalink were followed up to evaluate asthma-related morbidity measured by oral corticosteroid(OCS) initiation within 12 months of initiating LABAs, ICSs, or ICSs/LABAs. Asthma severity 12 months before drug initiation and during follow-up was adjusted as a time-varying variable via marginal structural models.
• Study status:
  Finalised

Research institutions and networks

Institutions

Ayad Ali

Study timelines

Date when funding contract was signed

Planned: 30/05/2010

Actual: 30/05/2010

Study start date

Planned: 01/07/2010

Actual: 01/07/2010

Date of final study report

Planned: 10/10/2012

Actual: 10/10/2012

Sources of funding

Other

More details on funding

University of Florida College of Pharmacy Perry A. Foote Eminent Scholar Chair Fund

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable