Effectiveness of an Interventional to Improve the Adequacy of the Indication of Lipid Lowering Treatment in Primary Prevention: Randomized Clinical Trial (Adequacy of Lipid Treatment)

Study type

• Study type:
  Clinical trial
• Scope of the study:
  Drug utilisation

Clinical trials

• Clinical trial randomisation:
  Randomised clinical trial

Study drug and medical condition

• Anatomical Therapeutic Chemical (ATC) code:
  (C10AA) HMG CoA reductase inhibitors

  HMG CoA reductase inhibitors

Population studied

• Age groups:
  Adults (18 to < 46 years)

  Adults (46 to < 65 years)

  Adults (65 to < 75 years)
• Estimated number of subjects:
  120000

Study design details

• Main study objective:
  To evaluate the impact of an international addressed to health professionals to improve the adequacy of lipid-lowering prescription in primary prevention of cardiovascular disease and reducing expenditure in the respect
• Outcomes:
  1.Description of demographic and clinical characteristics of patients with new lipid-lowering therapy.2. To know the adequacy of lipid-lowering therapy in patients with treatment for primary prevention (no history of cardiovascular disease).3. To Identify factors related to adequate pharmacological lipid-lowering treatment in primary prevention.4. To analyze the level of cardiovascular risk
• Data analysis plan:
  To assess the effect of the intervention model multilevel logistic regression analysis considering as dependent variable group intervention / control, adjusting for potential independent predictor variables and those considered clinically relevant, adjusting for baseline values ​​were performed