Effectiveness and safety of cardiac glycosides in HFrEF: target trial emulation and transportability of DIG and DIGIT-HF effects to a contemporary real-world population

ENCePP Code of conduct

Yes

Data sources

• Data source(s):
  Swedish Cause of Death Register

  Sweden National Prescribed Drugs Register / Läkemedelsregistret
• Data source(s), other:
  Swedish Heart Failure Registry (SwedeHF); Swedish National Patient Register (NPR); Swedish Longitudinal Integrated Database for Health Insurance and Labour (LISA); Swedish Total Population Register; DIG (DOI: 10.1056/NEJM19970220336080); DIGIT-HF (DOI: 10.1056/NEJMoa2415471)
• Data sources (types):
  Administrative healthcare records (e.g., claims)

  Clinical trial

  Death registry

  Disease registry

  Pharmacy dispensing records

  Population registry

Use of a Common Data Model (CDM)

• CDM mapping:
  No

Data quality specifications

• Check conformance:
  Yes
• Check completeness:
  Yes
• Check stability:
  Yes
• Check logical consistency:
  Yes

Data characterisation

• Data characterisation conducted:
  Not applicable