The effect of SGLT2 inhibitors among patients with Type 2 diabetes on the incidence of colorectal cancer

Study type

• Study topic:
  Disease /health condition
• Study type:
  Non-interventional study
• Scope of the study:
  Effectiveness study (incl. comparative)

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Anatomical Therapeutic Chemical (ATC) code:
  (A10BK) Sodium-glucose co-transporter 2 (SGLT2) inhibitors

  Sodium-glucose co-transporter 2 (SGLT2) inhibitors
• Medical condition to be studied:
  Colorectal cancer

Population studied

• Short description of the study population:
  Persons with Type 2 diabetes already using metformin, at least 30 years of age, who have never been diagnosed with cancer (excl. non-melanoma skin cancer) and have never been treated with SGLT2 inhibitors or DPP4 inhibitors (or GLP1 receptor agonists in supplementary analysis) before study entry
• Age groups:
  • Adult and elderly population (≥18 years)

    • Adults (18 to < 65 years)

      • Adults (18 to < 46 years)
      • Adults (46 to < 65 years)
    • Elderly (≥ 65 years)

      • Adults (65 to < 75 years)
      • Adults (75 to < 85 years)
      • Adults (85 years and over)