Registro Italiano Sclerosi Multipla e Patologie Correlate (Italian Multiple Sclerosis and Related Disorders Register)

First published 26/11/2025

Last updated 19/12/2025

Data source

Human

Disease registry

Population Qualitative Data

Population age groups: Paediatric Population (< 18 years)
Neonate
Preterm newborn infants (0 – 27 days)

Term newborn infants (0 – 27 days)

Infants and toddlers (28 days – 23 months)

Children (2 to < 12 years)

Adolescents (12 to < 18 years)

Adult and elderly population (≥18 years)
Adults (18 to < 65 years)
Adults (18 to < 46 years)

Adults (46 to < 65 years)

Elderly (≥ 65 years)
Adults (65 to < 75 years)

Adults (75 to < 85 years)

Adults (85 years and over)

Estimated percentage of the population covered by the data source in the catchment area: Approximately 70% of the Italian multiple sclerosis population and 40% of the NMOSD population are covered by RISM in Italy (prevalence estimates according to the document “Barometro della Sclerosi Multipla e Patologie Correlate 2025”, published by the Italian Multiple Sclerosis Patient Society – Associazione Italiana Sclerosi Multipla, AISM).

Description of the population covered by the data source in the catchment area whose data are not collected (e.g., people who are registered only for private care): Data from patients with multiple sclerosis or related disorders (NMOSD and MOGAD) are not collected if:
- patients do not provide informed consent;
- patients are not followed by a specialised multiple sclerosis clinical centre; or
- the specialised clinical centre does not participate in the RISM network of centres.

Population

Age group	Population size
Paediatric Population (< 18 years)	173
Adults (18 to < 65 years)	77829
Elderly (≥ 65 years)	18032

Median observation time

Median time (years) between first and last available records for unique individuals: 7.46

Secondary tabs