The Danish Multiple Sclerosis Registry

DMSR is a nationwide population-based disease registry encompassing comprehensive demographic and clinical information on persons with MS and related disorders (including CIS, RIS, NMOSD, and MOGAD).
Because notification on all patients with MS treated with disease-modifying drugs is mandatory, data on patients receiving disease-modifying drugs are virtually complete.
All treating clinics record data online on all patients with any of the above-mentioned demyelinating diseases. Notification starts when the disease is diagnosed; however, much attention is paid to anamnestic clarification of the time of clinical disease onset. During treatment, patients are monitored in connection with scheduled clinical visits at regular intervals with recording of demographic, clinical and paraclinical data, as well as Kurtzkes Expanded Disability Status Score (EDSS) and functional systems (FS) (Kurtzke, 1983), and side effects. Relapses are recorded with their dates and whether or not treatment with corticosteroid was applied. Notification of the DMSR is mandatory for all patients receiving DMT, and data collection is a part of the routine medical follow-up of patients. Failure of reporting mandatory data to the DMSR for a department will be observed by the health authorities who are the owners of the Danish public hospitals.