Drug utilisation and patient characterisation of statin usage

Study type

• Study topic:
  Human medicinal product
• Study type:
  Non-interventional study

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Name of medicine, other:
  Statins (HMG-CoA reductase inhibitors ATC C10AA)
• Anatomical Therapeutic Chemical (ATC) code:
  (C10AA) HMG CoA reductase inhibitors

  HMG CoA reductase inhibitors

Population studied

• Short description of the study population:
  General primary care population

Study design details

• Study design:
  Cohort and drug utilisation study covering the study period 2010 to 2023
• Main study objective:
  Objective 1: Incidence of prescriptions; 1a. What was the annual incidence of the prescription of individual statins and any statin, stratified by age group and sex?; 1b. What were the lines of therapy for incident statin users? I.e. what were the proportions of first, second and third line of treatment? ; ; Objective 2: Characterisation of statin users; 2a. What was the duration (mean, SD) of continuous individual statin and any statin prescriptions (non-incident), stratified by age, sex, or cardiovascular diagnosis?; 2b. What were the most common cardiovascular diagnoses, close to the initiation date, for each of the individual statins, and any statin (non-incident)?; 2c. In patients who were prescribed statins in the study period, which earlier statin(s) were they prescribed, up to 1 or 5 years before? And how many?;
• Setting:
  Primary care
• Outcomes:
  Exposure to Atorvastatin, Fluvastatin, Lovastatin (IQVIA DA DE only), Pitavastatin (IQVIA DA DE only), Pravastatin, Rosuvastatin, Simvastatin.