Study type

Study topic

Disease /health condition

Study type

Non-interventional study

Scope of the study

Disease epidemiology
Drug utilisation

Data collection methods

Secondary use of data
Non-interventional study

Non-interventional study design

Cohort
Population studied

Short description of the study population

The study population will include all individuals observed in one of the participating data sources during the study period (1st January 2010 to 31st December 2024) and having at least 1 year of database history.
For children within the age group of 0-<2 years, the need to have 365 days of prior database history will be dropped.

Age groups

  • Infants and toddlers (28 days – 23 months)
  • Children (2 to < 12 years)
  • Adolescents (12 to < 18 years)
Study design details

Study design

This study will use routinely collected health data from 4 databases in the DARWIN EU® network of data partners from 4 countries.
All databases were previously mapped to the OMOP CDM.
Data source
• Base de Datos para la Investigacíon Farmacoepidemiológica en el Ámbito Público (BIFAP), Spain (object

Main study objective

1. To describe the prevalence and incidence of HIV in the paediatric general population in a sample of European countries (Spain, Germany and Norway), overall and stratified by sex, age group (0-<1, 1-<2, 2-<5, 5-<12, 12-<18) and calendar year
2. To describe the prevalence and incidence of use of HIV-specific medication in the paediatric HIV population in a sample of European countries (Germany and Norway) particularly fixed-dose combinations, overall and stratified by sex, age group (0-<1, 1-<2, 2-<5, 5-<12, 12-<18) and calendar year.
3. To describe the prevalence and incidence of use of HIV-specific medication in the paediatric general population in a sample of European countries (Germany, Norway, and the United Kingdom) particularly fixed-dose combinations, overall and stratified by sex, age group (0-<1, 1-<2, 2-<5, 5-<12, 12-<18) and calendar year.