Real-world hospital treatment patterns in Belgium in early lung cancer between 2018 and 2023: a secondary data analysis [BE-LUNG]

Study type

• Study topic:
  Disease /health condition
• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology

  Drug utilisation
• Data collection methods:
  Secondary use of data

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Medical condition to be studied:
  Non-small cell lung cancer stage I

  Non-small cell lung cancer stage II

  Non-small cell lung cancer stage III

  Small cell lung cancer limited stage

Population studied

• Short description of the study population:
  Stage I-III non-small cell lung cancer and small cell lung cancer diagnosed between 1 January 2018 and 30 June 2023 with observation time until 31 December 2023
• Estimated number of subjects:
  1000

Study design details

• Study design:
  Multicenter study (n = 4) analyzing routinely collected data from pseudonymized electronic health records (EHRs) using natural language processing (NLP) for unstructured sources. The algorithm mapped variables to a standard terminology, generating OMOP CDM databases, validated per hospital.
• Main study objective:
  - Stage-specific biomarker testing (PD-L1, EGFR, ALK) ; - Stage-specific overall survival ; - Stage-specific treatment strategies
• Setting:
  Belgium, diagnosis between 2018 and 2023