Study type

Study topic

Disease /health condition

Study topic, other

Chronic skin conditions

Study type

Non-interventional study

Scope of the study

Disease epidemiology

Data collection methods

Secondary use of data
Non-interventional study

Non-interventional study design

Cohort
Study drug and medical condition

Medical condition to be studied

Acne
Psoriasis
Population studied

Short description of the study population

The study population will include all individuals present in the database during the study period (2010 to the most recent data available) and with at least one year of database history.
Within this population 2 sub-cohorts will be nested namely one on individuals newly diagnosed with acne and one consisting of individuals newly diagnosed with psoriasis.
Study design details

Study design

Population level cohort study

Main study objective

1. To assess the incidence rate of i) completed suicide, ii) attempted suicide, iii) suicide ideation, iv) intentional self-harm, v) suicide-related events (i.e. completed suicide, attempted suicide, and suicidal ideation), vi) composite outcomes (combination of all above mentioned events) in patients with acne stratified by sex, age category (12-<18 years, 18-30, 31-40, 41-50 etc, >=81 years), calendar year, and history of mental health disorders.
2. To assess the incidence rate of i) completed suicide, ii) attempted suicide, iii) suicide ideation, iv) intentional self-harm, v) suicide-related events (i.e. completed suicide, attempted suicide, and suicidal ideation), vi) composite outcomes (combination of all above mentioned events) before in patients with psoriasis stratified by sex, age category (12-<18 years, 18-30, 31-40, 41-50 etc, >=81 years), calendar year, and history of mental health disorders
3. To assess the incidence rate of i) completed suicide, ii) attempted suicide, iii) suicide ideation, iv) intentional self-harm, v) suicide-related events (i.e. completed suicide, attempted suicide, and suicidal ideation), vi) composite outcomes (combination of all above mentioned events) before in the general population stratified by sex, age category (12-<18 years, 18-30, 31-40, 41-50 etc, >=81 years), calendar year, and history of mental health disorders

Setting

This study will be conducted using routinely collected data from 5 primary and secondary care data sources in 5 European countries. All data were a priori mapped to the OMOP CDM.

Outcomes

Outcomes of interest are i) completed suicide, ii) attempted suicide, iii) suicide ideation or iv) intentional self-harm, v) suicide-related events (i.e. completed suicide, attempted suicide, and suicidal ideation), vi) composite outcomes (combination of all above mentioned events).
Documents
Study report
English (3.44 MB - PDF)View document