DARWIN EU® - Characterising interstitial lung disease in Europe

Study type

• Study topic:
  Disease /health condition
• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology
• Data collection methods:
  Secondary data collection

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Medical condition to be studied:
  Interstitial lung disease

Population studied

• Short description of the study population:
  All patients in the databases newly diagnosed with ILD in the period 1st January 2010 to 31st December 2022 with at least 365 days of data visibility prior to the date of first ILD diagnosis.
• Age groups:
  All

Study design details

• Study design:
  Cohort study with population-level descriptive epidemiology and patient-level characterisation
• Main study objective:
  The objectives are to measure (i) the incidences of ILD, stratified by age, sex and calendar time (obj. 1); (ii) to characterise the patients with ILD in terms of age, sex, comorbidities, risk factors and concomitant medications (obj. 2); and (iii) to measure the survival rates of patients diagnosed with ILD stratified by age, sex and calendar time (obj. 3) in four European countries. These objectives will be investigated for ILD overall and as well for the two most common ILD subtypes (alveolitis,/pneumonitis and lung fibrosis).
• Setting:
  This study will be conducted using routinely collected data from four databases in four European countries. All databases were previously mapped to the OMOP Common Data Model (CDM).