Study type

Study topic

Disease /health condition

Study type

Non-interventional study

Scope of the study

Disease epidemiology

Data collection methods

Secondary use of data
Non-interventional study

Non-interventional study design

Cohort
Study drug and medical condition

Medical condition to be studied

Chondrosarcoma
Population studied

Short description of the study population

The study population will include all individuals with a first diagnosis of chondrosarcoma identified in each database between 01/01/2010 and 31/12/2023. Participants with a diagnosis of cancer (any, excluding non-melanoma skin cancer) or enchondroma before the diagnosis of chondrosarcoma will be excluded.

Age groups

All
Paediatric Population (< 18 years)
Preterm newborn infants (0 – 27 days)
Term newborn infants (0 – 27 days)
Children (2 to < 12 years)
Adolescents (12 to < 18 years)
Adult and elderly population (≥18 years)
Adults (18 to < 65 years)
Adults (18 to < 46 years)
Adults (46 to < 65 years)
Elderly (≥ 65 years)
Adults (65 to < 75 years)
Adults (75 to < 85 years)
Adults (85 years and over)
Study design details

Study design

A retrospective cohort study of all newly diagnosed chondrosarcoma cases will be conducted.

Main study objective

To describe demographics, treatments, and overall survival of patients with incident chondrosarcoma, stratified by age, sex, study period, country/database, and, if available, by AJCC/UICC TNM stage categories and histological grade in 2010-2023.
The specific objectives of this study are:
1. To describe demographic characteristics (age and sex) of patients with chondrosarcoma at the time of diagnosis.
2. To describe chondrosarcoma treatment with medicines (chemotherapy and biologics) in patients that had undergone or not surgery, radiotherapy, both or neither.
3. To estimate the overall survival of newly diagnosed chondrosarcoma patients during the study period (2010-2023).

Setting

This study will use routinely collected health data from 6 nationwide and region-wide databases in 5 European countries.
Documents
Study report
English (1.97 MB - PDF)View document