Study type

Study type

Non-interventional study
Non-interventional study

Non-interventional study design

Cross-sectional
Population studied

Age groups

  • Adults (65 to < 75 years)
  • Adults (75 to < 85 years)
  • Adults (85 years and over)

Estimated number of subjects

530
Study design details

Main study objective

The main objectives of this study were to characterize institutionalized patients, systematically review their medication plans to detect potentially inappropriate medications, and to evaluate the impact of a multidisciplinary team intervention, with the inclusion of a clinical pharmacologist, on medication plans in nursing homes in Catalonia.

Outcomes

The primary outcomes will be to describe the patients health-related problems, prescribed pharmacological treatments, a comparative analysis of changes in the number of drugs, use of absorbents and whether the recommendations were followed. The secondary outcomes will be a descriptive analysis of incomplete data, the risk of interactions, therapeutic duplications, contraindications, drugs of doubtful efficacy, inappropriate drugs, recommendations made, withdrawn and added drugs, the number of drugs recommended to remove/change/adapt, along with the number of each one.

Data analysis plan

The data will be entered into a Research Electronic Data Capture (REDCap) platform. A quality analysis will be carried out prior to the descriptive and comparative analysis. The planned outcomes were the descriptive analysis according to clinical characteristics, chronic diseases and pharmacological treatments, the analysis of changes in the medication plan and the monitoring of proposals for changes. Continuous variables will be presented as means (standard deviation) or medians (interquartile range), and categorical variables as percentages. For the comparative analysis before-after post-intervention, we will carry out multiple comparisons.