DARWIN EU® Rates of occurrence of treatment-related intercurrent events in patients with major depressive disorder

Study type

• Study type:
  Non-interventional study

Non-interventional study

• Non-interventional study design:
  Cohort

Population studied

• Age groups:
  Adolescents (12 to < 18 years)

  Adults (18 to < 46 years)

  Adults (46 to < 65 years)

  Adults (65 to < 75 years)

  Adults (75 to < 85 years)

  Adults (85 years and over)
• Estimated number of subjects:
  19300000

Study design details

• Main study objective:
  To examine the proportion of patients with newly diagnosed major depressive disorder who start treatment with antidepressants and psycholeptics and of those the proportion who switch or discontinue treatment by specific timepoints after treatment initiation, stratified by age group, sex, and country.
• Outcomes:
  Treatment initiation, treatment discontinuation and treatment switch.
• Data analysis plan:
  Percentage of patients initiating treatment with specific antidepressants or psycholeptics. Percentage of patients switching treatment to specific antidepressants or psycholeptics. Percentage of patients discontinuing treatment with specific antidepressants or psycholeptics. Estimation of the mean, median, 25th percentile, 75th percentile, minimum, and maximum durations of antidepressant use.

Documents

Study report

DARWIN_EU_D2.2.4_Report_P2-C1-008_MDD_V5.1.pdf