Exacerbation history in COPD patients prior to diagnosis and subsequent treatment and outcomes

Study type

• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Medical condition to be studied:
  Chronic obstructive pulmonary disease

Population studied

• Age groups:
  • Adult and elderly population (≥18 years)

    • Adults (18 to < 65 years)

      • Adults (18 to < 46 years)
      • Adults (46 to < 65 years)
    • Elderly (≥ 65 years)

      • Adults (65 to < 75 years)
      • Adults (75 to < 85 years)
      • Adults (85 years and over)
• Estimated number of subjects:
  70000

Study design details

• Main study objective:
  To describe the number of exacerbations in the year prior to first COPD diagnosis, the patient’s characteristics at time of diagnosis, and the treatments and number of exacerbations by severity in the year following diagnosis
• Outcomes:
  The number of exacerbations following initial COPD diagnosis by severity, frequency and initial treatment
• Data analysis plan:
  Incident rate ratios will be calculated for any exacerbation/severe exacerbations and initial treatment following the index date.