Utilization of antidementia treatments: a large multinational-network population-based study.

Study type

• Study type:
  Non-interventional study
• Scope of the study:
  Drug utilisation

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Anatomical Therapeutic Chemical (ATC) code:
  (N06DA) Anticholinesterases

  Anticholinesterases

  (N06DX01) memantine

  memantine
• Medical condition to be studied:
  Dementia

Population studied

• Age groups:
  • Adult and elderly population (≥18 years)

    • Adults (18 to < 65 years)

      • Adults (46 to < 65 years)
    • Elderly (≥ 65 years)

      • Adults (65 to < 75 years)
      • Adults (75 to < 85 years)
      • Adults (85 years and over)
• Estimated number of subjects:
  81502

Study design details

• Main study objective:
  The aim of the present project is to characterize and assess the drug use of patients with dementia and the prescription of antidementia drugs (rivastigmine, galantamine, donepezil and memantine) in real-world data.
• Data analysis plan:
  Statistics: Yearly age-sex incidence rates (IR) and Kaplan Meier curves to assess the duration and drug discontinuation.