Incidence rates of Cutaneous T-Cell Lymphomas (CTCL) among patients with atopic dermatitis (AD)

Study type

• Study topic:
  Disease /health condition
• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology
• Data collection methods:
  Secondary use of data

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Medical condition to be studied:
  Cutaneous T-cell lymphoma

Population studied

• Short description of the study population:
  The study focused on general population in the UK and patients visiting general practices in Germany identified from the IMRD databases to determine the incidence rates of primary cutaneous T-cell lymphoma.
• Age groups:
  Adults (18 to < 46 years)

  Adults (46 to < 65 years)

  Adults (65 to < 75 years)

  Adults (75 to < 85 years)

  Adults (85 years and over)
• Special population of interest:
  Other
• Special population of interest, other:
  Patients with cutaneous T-cell lymphoma
• Estimated number of subjects:
  1000

Study design details

• Main study objective:
  This study aimed to estimate: i. incidence rates of cutaneous T-cell lymphomas (CTCL) in the general adult population ii. incidence rates of CTCL in adult patients with diagnosis of atopic dermatitis (AD) iii. incidence rates of CTCL in adult patients receiving treatment for severe AD
• Outcomes:
  Cutaneous T-cell lymphomas, Event rates for CTCL in the general population were stratified by sex, age group and year. Event rates among patients with AD were stratified by sex and age
• Data analysis plan:
  This is a cohort study describing population incidence rates of cutaneous T-cell lymphomas (CTCL), patient-level incidence rates of CTCL following diagnosis of atopic dermatitis (AD), and patient-level incidence rates of CTCL following treatment for severe AD.

Documents

Study results

FINAL-REPORT-AD and CTCL-Dec2022-for publication