Characteristics, Treatment and Healthcare Resource Utilisation in Patients diagnosed with Neuropathic or Chronic Pain Using Primary Care Electronic Health Records in the United Kingdom (UK)

Study type

• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Medical condition to be studied:
  Neuralgia

  Pain

Population studied

• Age groups:
  Adults (18 to < 46 years)

  Adults (46 to < 65 years)

  Adults (65 to < 75 years)

  Adults (75 to < 85 years)

  Adults (85 years and over)
• Estimated number of subjects:
  11700

Study design details

• Main study objective:
  To describe the characteristics and treatments for patients with a diagnosis of peripheral neuropathic pain, diabetic neuropathic pain, trigeminal neuralgia or chronic intractable pain in primary care in the UK.
• Outcomes:
  To estimate the HCRU and associated costs of managing patients with peripheral neuropathic pain, diabetic neuropathic pain, trigeminal neuralgia or chronic intractable pain in the UK.
• Data analysis plan:
  Descriptive Analyses All analyses will be descriptive and carried out using Microsoft SQL, R, Stata 14 (StataCorp LLC) and Microsoft Excel. Treatment, HCRU and costs will be summarised aggregating available patients’ follow-up as follows: a) By calendar year (e.g. 2017-2018) b) By 3-calendar years of data aggregated (e.g. 2017-2020) c) For the calendar years April 2019 – March 2020 and April 2020 – March 2021 separately to describe the pre- and post-COVID-19 periods. d) By number of patient-years since index pain diagnosis, at 1, 2, and 3 patient-year post-index date