Healthcare utilisation by patients with chronic cough

Study type

• Study topic:
  Disease /health condition
• Study type:
  Non-interventional study
• Scope of the study:
  Other
• If ‘other’, further details on the scope of the study:
  Healthcare resource utilisation
• Data collection methods:
  Primary data collection

Non-interventional study

• Non-interventional study design:
  Cross-sectional

Study drug and medical condition

• Medical condition to be studied:
  Cough

Population studied

• Short description of the study population:
  Consecutive patients with chronic cough (>8 weeks in duration) from a tertiary care specialist cough clinic (King’s College Hospital, London, UK) were evaluated between 2016 and 2018. The investigation, diagnosis, and management of chronic cough was assessed by clinicians according to the British Thoracic Society guidelines for the management of chronic cough in adults10. Inclusion criteria were a diagnosis of chronic cough, first attendance to a specialist cough clinic, and able to read and understand English. Exclusion criterion was respiratory tract infections within the preceding 4 weeks.
• Age groups:
  • Adults (18 to < 46 years)
  • Adults (46 to < 65 years)
  • Adults (65 to < 75 years)
  • Adults (75 to < 85 years)
  • Adults (85 years and over)
• Special population of interest:
  Other
• Special population of interest, other:
  Chronic cough patients
• Estimated number of subjects:
  100

Study design details

• Main study objective:
  Mean and range of total healthcare cost per patient related to assessment for chronic refractory cough both before and after attendance to the specialist clinic and the diagnosis of chronic refractory cough.
• Outcomes:
  Exploratory study of healthcare utilisation per patient with chronic cough, Association between healthcare utilisation and cough outcome measures.
• Data analysis plan:
  Resource use will be combined with appropriate unit costs from national sources, where possible (such as NHS reference costs). Resource use considered to be related to cough will be included. Predictive modelling of total and annual costs according to cough severity VAS and quality of life measure.