Study type

Study type

Non-interventional study

Scope of the study

Disease epidemiology
Non-interventional study

Non-interventional study design

Cohort
Cross-sectional
Study drug and medical condition

Medical condition to be studied

Asthma
Chronic obstructive pulmonary disease
Population studied

Age groups

Adults (18 to < 46 years)
Adults (46 to < 65 years)
Adults (65 to < 75 years)
Adults (75 to < 85 years)
Adults (85 years and over)

Estimated number of subjects

11556
Study design details

Main study objective

To identify different clinical phenotypes in a longitudinal real-world study of patients with asthma and COPD in primary care and hospitals setting. To study how health-related quality of life, disease control, exacerbations and mortality are affected by gender, treatment, multimorbidity and symptoms.

Outcomes

Exacerbations, mortality, quality of life (using MiniAQLQ, CCQ or EQ5-DL) and disease control (ACT, CAT or mMRC). Treatment use. Use and interpretation of spirometry. Comorbidity among patients with asthma and COPD compared to a gender and age-matched reference population.

Data analysis plan

Data processing is done in SPSS and STATA. Risk factors for primary outcome variables will be analyzed using various statistical methods such as logistic regression and Cox regression. For factors affecting health-related quality of life, multiple linear regression will be used. For data-driven cluster analysis, pam algorithm is used.
Documents
Study, other information
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