A Global Cross-sectional Survey to Capture Awareness and Knowledge of Mesenchymal Stem Cell (MSC) Therapy by Gastroenterologists and Colorectal Surgeons

Study type

• Study topic:
  Other
• Study topic, other:
  Disease/Epidemiology study
• Study type:
  Non-interventional study
• Scope of the study:
  Other
• If ‘other’, further details on the scope of the study:
  Knowledge and attitudes
• Data collection methods:
  Primary data collection

Non-interventional study

• Non-interventional study design:
  Cross-sectional

Population studied

• Short description of the study population:
  Study participants were gastroenterologists and colorectal surgeons identified using IQVIA’s proprietary comprehensive database containing investigator specialty and contact details for physicians that are involved in research but also physicians not involved in research. In total, 387 gastroenterologists and colorectal surgeons were targeted to be enrolled in 15 countries'. Sampling per country was weighted to reflect estimates of prevalence of CD per country and country population size and efforts were made to ensure recruitment from different sites and from each type of institution, to increase generalizability of findings.; Inclusion criteria:; • Physicians must be currently practicing registered gastroenterologists or colorectal surgeons and; • Physicians must be practicing within one of the in-scope countries; Exclusion criteria; • There were no specific exclusion criteria for this survey.
• Age groups:
  • Adult and elderly population (≥18 years)

    • Adults (18 to < 65 years)

      • Adults (18 to < 46 years)
      • Adults (46 to < 65 years)
    • Elderly (≥ 65 years)

      • Adults (65 to < 75 years)
      • Adults (75 to < 85 years)
      • Adults (85 years and over)
• Estimated number of subjects:
  387

Study design details

• Main study objective:
  To quantitatively describe current perspectives, awareness, and current knowledge state (including knowledge about mechanism of action) of MSC therapy amongst gastroenterologists and colorectal surgeons.
• Outcomes:
  Primary outcome will include the quantitative description of the sociodemographic and clinical experience characteristics, level of awareness, and current knowledge of MSCs amongst gastroenterologists and colorectal surgeons by type of institution and geographic regions worldwide, their main concerns related to MSC application, and the willingness to use MSC therapy in clinical practice setting.
• Data analysis plan:
  Descriptive statistics and/or listings will be used. Continuous variables will be summarized by number of participants n, mean, standard deviation, median, minimum, maximum, first quartile, and third quartile. Categorical variables will be summarized by n and percentage of participants in each category. Missing data will not be imputed, and all analyses will be based on participants with no missing data only.