Study type

Study type

Non-interventional study

Scope of the study

Assessment of risk minimisation measure implementation or effectiveness
Disease epidemiology
Drug utilisation
Study drug and medical condition

Anatomical Therapeutic Chemical (ATC) code

(N05B) ANXIOLYTICS
ANXIOLYTICS
(N05A) ANTIPSYCHOTICS
ANTIPSYCHOTICS
(N06A) ANTIDEPRESSANTS
ANTIDEPRESSANTS
(N06BX) Other psychostimulants and nootropics
Other psychostimulants and nootropics
(N05AN) Lithium
Lithium
(N07A) PARASYMPATHOMIMETICS
PARASYMPATHOMIMETICS

Medical condition to be studied

Suicide attempt
Completed suicide
Population studied

Age groups

Term newborn infants (0 – 27 days)
Infants and toddlers (28 days – 23 months)
Children (2 to < 12 years)
Adolescents (12 to < 18 years)

Estimated number of subjects

100000
Study design details

Main study objective

The main objective of the PaEDiatric IMPact of terrorist AttaCks in general populaTion (PEDIMPACT) Study is to evaluate the short- and middle-term impact in children and adolescents of the terror attack in Nice on July 14th, 2016 on use of mental health resources namely 1) use of psychotropic medications and 2) mental health-related hospitalizations and 3) outpatient visits.

Outcomes

1) use of psychotropic medications and 2) mental health-related hospitalizations and 3) outpatient visits.

Data analysis plan

This is a population-based retrospective cohort study using data from the French National Health Data System (Système National des Données de Santé SNDS) collected from January 1, 2012, to 31 December 2021, in the pediatric population. We will conduct a quasi-experimental study using a monthly interrupted-time series analysis (based on mean-dispersion negative binomial regression models, segmented time series models and an autoregressive integrated moving average ARIMA models) to estimate the short- and middle-term impact on mental health service use in the Nice geographic region vs. three control regions, after the Nice truck-ramming attack.