Clinical characteristics and disease burden of patients with diabetes mellitus combined with cardiovascular or chronic kidney disease based on regional medical database in Tianjin China

Study type

• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology

  Other
• If ‘other’, further details on the scope of the study:
  Description of clinical characteristics, treatment and economic burden of disease

Non-interventional study

• Non-interventional study design:
  Cross-sectional

Population studied

• Age groups:
  Adults (18 to < 46 years)

  Adults (46 to < 65 years)

  Adults (65 to < 75 years)

  Adults (75 to < 85 years)

  Adults (85 years and over)
• Estimated number of subjects:
  100000

Study design details

• Main study objective:
  The study aimsed to investigate the clinical characteristics, treatment, and economic burden of disease of Chinese diabetic /non-diabetic patients with/without established cardiovascular disease, chronic kidney disease, or at high cardiovascular risk
• Outcomes:
  1) The proportion of diabetic/non-diabetic patients with established CVD, or CKD, or at high cardiovascular risk 2) The proportion of diabetic patients with established CVD, or CKD, or at high cardiovascular risk among all diabetic patients 3) The proportion of non-diabetic patients with established CVD, or CKD, or at high cardiovascular risk, 1) Age at admission at the latest visit for all patients, as well as the trends for inpatients over time (2015, 2017, and 2019) 2) Gender at the latest visit for all patients, as well as the trends for inpatients over time (2015, 2017, and 2019) 3) Insurance payment at the latest visit for all patients, as well as the trends for inpatients over time (2015, 2017, and 2019)
• Data analysis plan:
  Before analyses start, 200 randomly selected medical chart will be fully reviewed by well-trained experts to validate the accuracy and sensibility of code used to identify patients with cardiovascular disease or at high cardiovascular risk. The analyses will mainly describe the patient demographic characteristics, comorbidities, complications, treatment pattern and economic burden based on 40 hospitals EMRs of Tianjin regional database. Descriptive data will be provided. Characteristics presented as continuous data will be summarized through means, standard deviations, medians, minimum and maximum values, whereas, categorical data will be summarized as counts and proportions.