REACT-SCOT Pharmacoepidemiology (REACT-SCOT-PHARM)

Study type

• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology

Non-interventional study

• Non-interventional study design:
  Case-control

Study drug and medical condition

• Medical condition to be studied:
  COVID-19

Population studied

• Age groups:
  • Term newborn infants (0 – 27 days)
  • Infants and toddlers (28 days – 23 months)
  • Children (2 to < 12 years)
  • Adolescents (12 to < 18 years)
  • Adults (18 to < 46 years)
  • Adults (46 to < 65 years)
  • Adults (65 to < 75 years)
  • Adults (75 to < 85 years)
  • Adults (85 years and over)
• Estimated number of subjects:
  30000

Study design details

• Main study objective:
  A systematic examination of drug exposures and their association with severe COVID-19
• Outcomes:
  Severe COVID -19 defined as entry to critical care unit or death within of a positive nucleic acid test for SARS-CoV-2
• Data analysis plan:
  rate ratios estimated by conditional logistic regression