Patient´s perspective: emotional impact of the COVID-19 pandemic in psoriasis patients treated with biological drugs and small molecules in real clinical practice

Study type

• Study topic:
  Human medicinal product

  Disease /health condition
• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology

  Drug utilisation
• Data collection methods:
  Combined primary data collection and secondary use of data

Non-interventional study

• Non-interventional study design:
  Cross-sectional

  Other
• Non-interventional study design, other:
  Retrospective study

Study drug and medical condition

• Anatomical Therapeutic Chemical (ATC) code:
  (L04AC13) ixekizumab

  ixekizumab

  (L04AC13) ixekizumab

  ixekizumab

  (L04AC10) secukinumab

  secukinumab

  (L04AA32) apremilast

  apremilast

  (L04AB04) adalimumab

  adalimumab

  (L04AC16) guselkumab

  guselkumab
• Medical condition to be studied:
  Psoriasis

Population studied

• Short description of the study population:
  Psoriasis patients under treatment in our Hospital during the last year. Inclusion criteria were psoriasis being under biologics or small molecules during the onset and the development of the crisis, verbal consent and adulthood. Exclusion criteria included impossibility of telephone contact or refusal to participate.
• Age groups:
  • Adult and elderly population (≥18 years)

    • Adults (18 to < 65 years)

      • Adults (18 to < 46 years)
      • Adults (46 to < 65 years)
    • Elderly (≥ 65 years)

      • Adults (65 to < 75 years)
      • Adults (75 to < 85 years)
      • Adults (85 years and over)
• Special population of interest:
  Immunocompromised
• Estimated number of subjects:
  174

Study design details

• Main study objective:
  We sought to clarify the status of patients on immunosuppressive or immunomodulator drugs with respect to possible COVID-19 involvement and to detect changes in their treatment regimen, the reason why they made them as well as the influence in their social behaviour.
• Data analysis plan:
  A statistical analysis was performed with chi-squared, Fisher exact tests and Student’s t-test using Statistical Package for Social Sciences (SPSS®) for Windows, version 25.0 (Armonk, NY: IBM Corp).