Study type

Study type

Non-interventional study

Scope of the study

Other

If ‘other’, further details on the scope of the study

Risk for ventilator and ECMO needs in patients with pneumonia
Non-interventional study

Non-interventional study design

Cohort
Study drug and medical condition

Medical condition to be studied

Pneumonia
Population studied

Age groups

  • Preterm newborn infants (0 – 27 days)
  • Term newborn infants (0 – 27 days)
  • Infants and toddlers (28 days – 23 months)
  • Children (2 to < 12 years)
  • Adolescents (12 to < 18 years)
  • Adults (18 to < 46 years)
  • Adults (46 to < 65 years)
  • Adults (65 to < 75 years)
  • Adults (75 to < 85 years)
  • Adults (85 years and over)

Estimated number of subjects

10000
Study design details

Main study objective

Characterize patients with pneumonia and identify risk factors for ventilator/ECMO need, prolonged ventilator use and mortality

Outcomes

- Evaluate patient demographics, comorbidities, prescription medications and concurrent diagnoses at time of first pneumonia diagnosis (by pneumonia type) - Evaluate patient healthcare utilization and risk of requiring critical-care – including extracorporeal membrane oxygenation (EMO) - mortality, in patients with viral vs other pneumonia (by pneumonia types), - Evaluate risk of patients with a first viral pneumonia diagnosis to also develop other pneumonia types - Evaluate patient demographics, comorbidities, prescription medications, and risk factors for critical-care and mortality in patients with a pneumonia, by type

Data analysis plan

Descriptive statisticsComparison between pneumonia types (chi square for categorical variable comparison, t-test for continuous variable comparisonLogistic models to evaluate risks for critical care needs and mortality. Regression models to evaluate duration of disease