Study type

Study type

Non-interventional study

Scope of the study

Drug utilisation
Non-interventional study

Non-interventional study design

Cohort
Study drug and medical condition

Anatomical Therapeutic Chemical (ATC) code

(N06BA) Centrally acting sympathomimetics
(N06A) ANTIDEPRESSANTS
(N05A) ANTIPSYCHOTICS
(N05B) ANXIOLYTICS
(N05C) HYPNOTICS AND SEDATIVES

Medical condition to be studied

Psychiatric investigation
Population studied

Age groups

Term newborn infants (0 – 27 days)
Infants and toddlers (28 days – 23 months)
Children (2 to < 12 years)
Adolescents (12 to < 18 years)

Estimated number of subjects

300000
Study design details

Main study objective

To describe the use of psychotropic drugs in children <18 years from Catalonia during 2007-2017.To describe the psychiatric diagnoses in the <18 years population consuming psychotropic drugs.To describe the consumption pattern and characteristics of patients <18 years who start treatment with psychotropic drugs.

Data analysis plan

All data management, purification, descriptive calculation and statistical analysis processes will be carried out using the statistical package R 3.3(2016)Demographic data and baseline characteristics of the population will be described by relative and absolute frequencies for the categorical variables and median standard deviation or median and interquartile range for the continuous variables.In the bivariate analysis, Chi-square test or the exact Fischer test for the categorical variables and the t-test of Student or the U-test of Mann-Whitney for the continuous variables according to their distributionEvaluation of psychotropic consumption based on psychiatric/obstetric maternal records, as well as the risk related to the persistence/adherence of these in patients with an age range of 16 to 18 years old, will be performed using multiple logistic regression models or proportional risk models (Cox).Adjustment for risk factors based on the characteristics of the study population