Randomised Controlled Trial (RCT) vs Real Life initiative (RCT vs Real Life)

Study type

• Study topic:
  Disease /health condition
• Study type:
  Not applicable
• If ‘Not applicable’, further details on the study type:
  Systematic evaluation study
• If ‘other’, further details on the scope of the study:
  Review /evaluation other studies

Study drug and medical condition

• Medical condition to be studied:
  Chronic obstructive pulmonary disease

Population studied

• Short description of the study population:
  Patients with COPD in the Optimum Patients Care Research database (OPCRD) who would meet the inclusion and exclusion criteria to participate in recent RCTs of inhaled long-acting bronchodilator therapy
• Age groups:
  Adults (46 to < 65 years)

  Adults (65 to < 75 years)

  Adults (75 to < 85 years)

  Adults (85 years and over)
• Special population of interest:
  Other
• Special population of interest, other:
  Chronic obstructive pulmonary disease (COPD) patients
• Estimated number of subjects:
  36893

Study design details

• Main study objective:
  To determine the proportion of patients with COPD in the Optimum Patients Care Research database (OPCRD) who would meet the inclusion and exclusion criteria to participate in recent RCTs of inhaled long-acting bronchodilator therapy.
• Data analysis plan:
  Description of percentages of total OPCRD population of patients with COPD who would be eligbile for RCTs.Compare characteristics of eligible OPCRD population with reported characteristics of patients participating to RCT

Documents

Study publications

Halpin, D.M., Kerkhof, M., Soriano, J.B., Mikkelsen, H. and Price, D.B., 2016. …