Benzodiazepine and anticholinergic use and incident dementia (ABCD study)

Study identification

• PURI:
  https://redirect.ema.europa.eu/resource/27156
• EU PAS number:
  EUPAS8705
• Study ID:
  27156
• Official title and acronym:
  Benzodiazepine and anticholinergic use and incident dementia (ABCD study)
• DARWIN EU® study:
  No
• Study countries:
  United Kingdom
• Study description:
  In this study we will examine whether the use of benzodiazepines, non-benzodiazepine derivates and medications with anticholinergic activity increase the risk of dementia. We will also examine whether the risk persists or is reduced once the medication is stopped. We will identify CPRD patients who, since April 2006, were diagnosed with dementia aged 65-99 years. We will compare the medication history of each patient with dementia to that of 7 matched patients without dementia. We will compare the use and dosage of medications prescribed during the period before dementia diagnosis, whilst controlling for other health and social differences.
• Study status:
  Ongoing

Research institutions and networks

Institutions

University of East Anglia

Study timelines

Date when funding contract was signed

Actual: 30/06/2014

Study start date

Actual: 03/07/2015

Data analysis start date

Planned: 24/08/2015

Actual: 26/10/2015

Date of final study report

Planned: 30/09/2018

Sources of funding

Non-for-profit organisation (e.g. charity)

More details on funding

Alzheimer's Society

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable