Antidepressants during pregnancy: a French drug utilisation study in EFEMERIS cohort

Study type

• Study topic:
  Disease /health condition

  Human medicinal product
• Study type:
  Non-interventional study
• Scope of the study:
  Drug utilisation
• Data collection methods:
  Secondary use of data

Study drug and medical condition

• Anatomical Therapeutic Chemical (ATC) code:
  (N06AA) Non-selective monoamine reuptake inhibitors

  Non-selective monoamine reuptake inhibitors

  (N06AB) Selective serotonin reuptake inhibitors

  Selective serotonin reuptake inhibitors

  (N06AF) Monoamine oxidase inhibitors, non-selective

  Monoamine oxidase inhibitors, non-selective

  (N06AG) Monoamine oxidase A inhibitors

  Monoamine oxidase A inhibitors

  (N06AX) Other antidepressants

  Other antidepressants
• Medical condition to be studied:
  Depression

Population studied

• Short description of the study population:
  Pregnant women, who were pregnant from 2005 to 2014 in Haute-Garonne.
• Age groups:
  Adults (18 to < 46 years)
• Special population of interest:
  Pregnant women
• Estimated number of subjects:
  89000

Study design details

• Main study objective:
  The main objective is to describe the use of antidepressants during pregnancy in France.
• Outcomes:
  Dispensation of antidepressant drugs.
• Data analysis plan:
  Prevalence and incidence of AD prescriptions during pregnancy, characteristics of AD users, and trends in AD use over the 10-year period were studied.