A mixed methods observational study to evaluate the implementation of a smartphone software application (App) and computerised decision-support system (CDSS) for antibiotic treatment guidelines in 50 NHS hospitals and to explore its potential impact on trends in antibiotic prescribing, resistance and inpatient clinical outcomes using interrupted time series analysis (The MicroGuide Study)

Study identification

• PURI:
  https://redirect.ema.europa.eu/resource/19014
• EU PAS number:
  EUPAS19013
• Study ID:
  19014
• Official title and acronym:
  A mixed methods observational study to evaluate the implementation of a smartphone software application (App) and computerised decision-support system (CDSS) for antibiotic treatment guidelines in 50 NHS hospitals and to explore its potential impact on trends in antibiotic prescribing, resistance and inpatient clinical outcomes using interrupted time series analysis (The MicroGuide Study)
• DARWIN EU® study:
  No
• Study countries:
  United Kingdom
• Study description:
  Mixed methods design to include survey and qualitative interviews with NHS staff and exploratory analysis of quantitative outcome variables pre- and post-implementation of the intervention using time series analysis of hospital-level data
• Study status:
  Planned

Research institutions and networks

Institutions

University of Southampton

Study timelines

Date when funding contract was signed

Planned: 30/06/2017

Study start date

Planned: 31/07/2017

Date of final study report

Planned: 28/09/2018

Sources of funding

Pharmaceutical company and other private sector 

More details on funding

MSD

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable