Study identification

EU PAS number

EUPAS32482

Study ID

32483

Official title and acronym

Exploring differences in asthma disease severity and pathways: variation by ethnicity and socioeconomic status

DARWIN EU® study

No

Study countries

United Kingdom

Study description

This is a retrospective cohort study using data from English general practices registered with the OPCRD. The specific aims are to:• Explore differences in asthma severity, asthma control and asthma phenotype by ethnic and socioeconomic groups• Explore patterns of medication usage and healthcare utilisation (scheduled and unscheduled) for asthma in different ethnic and socioeconomic groups• To identify determinants of asthma severity in different ethnic and socioeconomic groups• Investigate disparities in referral patterns for patients from different ethnic and socioeconomic groups thnicity will be identified from GP ad/or HES records. Socioeconomic Status will be measured using Index of Multiple Deprivation. Asthma severity (assessed using medications), lung function, blood eosinophils, medication adherence, healthcare utilisation and specialist referral will be ascertained from GP records.Descriptive statistics will be calculated for the entire cohort and for each ethnic and socioeconomic group separately. Multivariable analysis accounting for differences in demographic and lifestyle factors (e.g. BMI, Smoking) will be conducted using appropriate regression models.

Study status

Planned
Research institutions and networks

Institutions

Contact details

Busby John

Primary lead investigator

Study timelines

Date when funding contract was signed

Planned:

Study start date

Planned:

Date of final study report

Planned:
Sources of funding
Other

More details on funding

No external funding
Regulatory

Was the study required by a regulatory body?

No

Is the study required by a Risk Management Plan (RMP)?

Not applicable