Characteristics and Treatment Patterns of Patients with Chronic Obstructive Pulmonary Disease (COPD), Initiating Tio+Olo or Other Maintenance Therapies in the US and the UK: A Retrospective Claims Database Study.

Study type

• Study type:
  Non-interventional study
• Scope of the study:
  Disease epidemiology

Non-interventional study

• Non-interventional study design:
  Cohort

Study drug and medical condition

• Medical condition to be studied:
  Chronic obstructive pulmonary disease

Population studied

• Age groups:
  Adults (18 to < 46 years)

  Adults (46 to < 65 years)

  Adults (65 to < 75 years)

  Adults (75 to < 85 years)

  Adults (85 years and over)
• Estimated number of subjects:
  350000

Study design details

• Main study objective:
  The primary objectives of the study are to use US and UK data to describe the characteristics of COPD patients according to various demographic, lifestyle, clinical, and medication use at the time of diagnosis, at the time of initiation of first mantenance therapy and at the time of initiation of second maintenance therapy
• Outcomes:
  Patient characteristics, include various demographic, lifestyle, clinical, and medication characteristics will be reported at three points in time: 1) COPD claim confirming diagnosis date (Cohort Entry Date), 2) Date of initiation of first maintenance therapy (1st Treatment Index Date), overall and stratified by therapy category, 3)
• Data analysis plan:
  • All covariates will be reported as mean (SD) and/or median (IQR) for continuous variables and counts and frequency (%) for categorical variables.