Underuse of beta-blockers in patients with heart failure and COPD

Study type

• Study topic:
  Disease /health condition

  Human medicinal product
• Study type:
  Non-interventional study
• Scope of the study:
  Drug utilisation
• Data collection methods:
  Secondary use of data

Non-interventional study

• Non-interventional study design:
  Cross-sectional

Study drug and medical condition

• Anatomical Therapeutic Chemical (ATC) code:
  (C07) BETA BLOCKING AGENTS

  BETA BLOCKING AGENTS

  (C09) AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM

  AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
• Medical condition to be studied:
  Chronic obstructive pulmonary disease

  Cardiac failure

Population studied

• Short description of the study population:
  Patients with heart failure (HF) who also have chronic obstructive pulmonary disease (COPD).
• Age groups:
  • Adult and elderly population (≥18 years)

    • Adults (18 to < 65 years)

      • Adults (18 to < 46 years)
      • Adults (46 to < 65 years)
    • Elderly (≥ 65 years)

      • Adults (65 to < 75 years)
      • Adults (75 to < 85 years)
      • Adults (85 years and over)
• Special population of interest:
  Other
• Special population of interest, other:
  Chronic obstructive pulmonary disease (COPD) and cardiac failure patients
• Estimated number of subjects:
  125000

Study design details

• Main study objective:
  To assess the real life use of beta-blockers for patients with HF who also have COPD
• Data analysis plan:
  Treatments for HF will be compared between groups using multinomial logistic regression, and the odds ratios, 95% confidence intervals, and p-values will be reported.