Metabolic changes in obese patients with diabetes mellitus - impact of weight reduction

Study summary

No information provided.

Study identification

• EU PAS number:
  EUPAS8455
• Study ID:
  8456
• Official title and acronym:
  Metabolic changes in obese patients with diabetes mellitus - impact of weight reduction
• DARWIN EU® study:
  No
• Study countries:
  Czechia
• Study description:
  We estimated metabolic parameters of obese type 1 diabetics and compared them with subgroup of lean patients with diabetes mellitus type 1. We characterised the dynamic of metabolic parameters in obese type 1 diabetics during our weight reduction programme with acute and chronical phase of weight reduction. Measurements were done before (Phase I), after a month (Phase II) (one week of fasting in the hospital setting and three weeks on a diet containing 150g saccharides per day) and after one year (Phase III) on a diet with 225g saccharides per day. The main observed characteristics were: anthropometry, body composition, diabetes compensation, insulin resistance, markers of cholesterol metabolism, adipokines.
• Study status:
  Finalised

Research institutions and networks

Institutions

University Hospital Hradec Králové

Study timelines

Date when funding contract was signed

Planned:18/08/2008

Actual:18/08/2008

Study start date

Planned:02/02/2009

Actual:04/02/2008

Data analysis start date

Planned:04/08/2009

Actual:05/05/2009

Date of final study report

Planned:06/02/2012

Actual:06/02/2012

Sources of funding

Other

More details on funding

University Hospital in Hradec Kralove, MH CZ-DRO (UHHK, 00179906)

Regulatory

• Was the study required by a regulatory body?:
  No