DEVELOPMENT AND VALIDATION OF A SHORTENED VERSION OF THE SPANISH QUALITY OF LIFE QUESTIONNAIRE FOR INFLAMMATORY BOWEL DISEASE

Study type

• Study topic:
  Disease /health condition
• Study type:
  Non-interventional study
• Scope of the study:
  Other
• If ‘other’, further details on the scope of the study:
  Development of a questionnaire for health related quality of life assessment
• Data collection methods:
  Combined primary data collection and secondary use of data

Non-interventional study

• Non-interventional study design:
  Cross-sectional

Study drug and medical condition

• Medical condition to be studied:
  Crohn's disease

  Inflammatory bowel disease

Population studied

• Short description of the study population:
  Patients with ulcerative colitis and Crohn’s disease
• Age groups:
  Adults (18 to < 46 years)

  Adults (46 to < 65 years)
• Special population of interest:
  Other
• Special population of interest, other:
  Ulcerative colitis and Crohn’s disease patients
• Estimated number of subjects:
  311

Study design details

• Main study objective:
  To elaborate and validate a short quality-of-life questionnaire with the most representative items from the Spanish version of the 36-item Inflammatory Bowel Disease Questionnaire (IBDQ-36) using the Rasch analysis
• Data analysis plan:
  The responses to 311 IBDQ-36 questionnaires from 167 patients with ulcerative colitis (UC) and 144 with Crohn's disease (CD) were analyzed. IBDQ-36 was shortened with successive Rasch analyses until all the remaining items showed acceptable separation and goodness-of-fit properties. Validation of the short questionnaire was studied in a new group of 125 patients by determining its validity and reliability.

Documents

Study publications

Alcalá MJ, Casellas F, Fontanet G, Prieto L, Malagelada JR. Shortened questionn…

Casellas F, Alcalá MJ, Prieto L, Miró JR, Malagelada JR. Assessment of the infl…