PGRx®

PGRx®A unique Case-Referent Information Database for the Benefits & Risks of Medicinesis based on a systematisation of the case-referent (or case-control) methodology. PGRx ® is a unique approach to the study of infrequent or delayed events potentially associated with adverse events or beneficial outcomes of drug use (routine collection of 300+ drugs,vaccines and lifestyle factors).In brief,PGRx® collects: 1) Cases of different diseases of interest (MS,Guillain-Barré syndrome,lupus,myositis,RA,diabetes type 1,autoimmune thyroiditis,ITP,Graves disease,Torsade de pointes,first myocardial infarction,depression,suicide attempts,cancer). Cases are recruited from networks of specialised centres in France,UK,Canada,and shortly in and other European countries. 2) A pool of referents representative of patients in general practice (stratified by gender,age and region) is collected by wide networks of GPs. Referents are selected by relevant criteria and matched to the cases.