Impact of medication adherence on mortality and cardiovascular morbidity: a population-based retrospective cohort study. IMPACT study

Study identification

• PURI:
  https://redirect.ema.europa.eu/resource/47985
• EU PAS number:
  EUPAS19017
• Study ID:
  47985
• Official title and acronym:
  Impact of medication adherence on mortality and cardiovascular morbidity: a population-based retrospective cohort study. IMPACT study
• DARWIN EU® study:
  No
• Study countries:
  Spain
• Study description:
  Cohort study with electronic health records in Primary Healthcare in order to assess the risk of major cardiovascular events and all-cause mortality according to the level of adherence to antiplatelet agents, betablockers, ACEI or ARB, and statins, in a population of incident cases of CHD, defined as patients with a first episode of acute coronary syndrome (ACS). This is a population-based retrospective cohort study of patients with a first episode of ACS registered in CMBD-HA of the ICS from 2006 to 2015.
• Study status:
  Finalised

Research institution and networks

Institutions

Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina, IDIAPJGol

Spain

Contact details

Giner-Soriano Maria

Study contact

[e-mail]

Giner-Soriano Maria

Primary lead investigator

Study timelines

Date when funding contract was signed

Planned: 30/03/2017

Actual: 30/03/2017

Data collection

Planned: 03/07/2017

Actual: 02/10/2017

Start date of data analysis

Planned: 02/10/2017

Actual: 08/01/2018

Date of final study report

Planned: 31/12/2020

Actual: 31/12/2020

Sources of funding

Other

More details on funding

IDIAP Jordi Gol

Study protocol

Initial protocol

IMPACT study Protocol 2.0_ENCePP

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable