Study identification

EU PAS number

EUPAS8205

Study ID

47380

Official title and acronym

Risk of subsequent cardiovascular events in patients discharged after myocardial infarction - Perseus (PERSEUS)

DARWIN EU® study

No

Study countries

Finland

Study description

Myocardial infarction affects about 5000 patients in Finland per year. Almost 20% of them die within one year after the event. Among the Nordic countries, cardiovascular death rates are the highest in Finland. Current guidelines advise to treat myocardial infarction patients with 12-month dual antiplatelet treatment. An ongoing PEGASUS-TIMI 54 clinical study aims to survey the advantages of longer use of ticagrelor and acetylsalicylic acid in secondary prevention. The aim of the present study is to describe the risk development and risk factors of subsequent cardiovascular events in patients discharged from hospital after myocardial infarction. The study questions focus on patients surviving more than one year without subsequent myocardial infarction or stroke and on patients with known additional risk factors. Pre-specified subgroup analyses in populations mimicking the PEGASUS-TIMI 54 study population in a real-life setting will be performed to enable comparison of real-life and randomised study settings.

Study status

Finalised
Research institutions and networks

Institutions

IQVIA
United Kingdom
First published:
22/04/2024
Institution Non-Pharmaceutical company ENCePP partner

Contact details

Massoud Toussi

Primary lead investigator

Study timelines

Date when funding contract was signed

Actual:

Study start date

Planned:
Actual:

Data analysis start date

Planned:
Actual:

Date of final study report

Planned:
Actual:
Sources of funding
Pharmaceutical company and other private sector 

More details on funding

AstraZeneca Nordic Baltic
Regulatory

Was the study required by a regulatory body?

No

Is the study required by a Risk Management Plan (RMP)?

Not applicable