Similarity-based approaches to identifying risk of future asthma attack using UK primary care data

Study identification

• PURI:
  https://redirect.ema.europa.eu/resource/36060
• EU PAS number:
  EUPAS36059
• Study ID:
  36060
• Official title and acronym:
  Similarity-based approaches to identifying risk of future asthma attack using UK primary care data
• DARWIN EU® study:
  No
• Study countries:
  United Kingdom
• Study description:
  Our aim is to investigate similarity-based approaches to identify the risk of a patient having an asthma attack in the 1 year following an asthma review appointment in primary care. We will use primary care electronic health records to derive this model. The two similarity-based approaches that we will investigate are a neighbourhood approach (i.e. identifying the patients who are most similar to the patient of interest and training the model only on these patients) and a cluster approach (i.e. identifying groups of similar patients via cluster analysis and training a separate model for each group). The variables that we will use to quantify similarity and derive the risk score will be chosen based on similar risk-prediction studies in asthma.
• Study status:
  Planned

Research institution and networks

Institutions

University of Edinburgh

United Kingdom

Networks

Optimum Patient Care (OPC) Network

United Kingdom (Northern Ireland)

Asthma UK Centre for Applied Research

Study timelines

Date when funding contract was signed

Planned: 18/08/2020

Study start date

Planned: 18/08/2020

Data analysis start date

Planned: 18/08/2020

Date of interim report, if expected

Planned: 30/06/2021

Date of final study report

Planned: 31/12/2021

Sources of funding

Other

More details on funding

MRC (via PhD studentship)

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable