COMPARABILITY OF POPULATION DEFINITIONS WITHIN & BETWEEN GLOBAL DATABASES – DEVELOPING TOOLS FOR OBSERVATIONAL RESEARCH (ACO Population Definitions)

Study identification

• EU PAS number:
  EUPAS13959
• Study ID:
  31039
• Official title and acronym:
  COMPARABILITY OF POPULATION DEFINITIONS WITHIN & BETWEEN GLOBAL DATABASES – DEVELOPING TOOLS FOR OBSERVATIONAL RESEARCH (ACO Population Definitions)
• DARWIN EU® study:
  No
• Study countries:
  Korea, Democratic People's Republic of

  Netherlands

  Poland

  Spain

  United Kingdom
• Study description:
  This initial phase—the focus of this study—intends to compare prevalence and agreement rates for the different ACO definitions between different national and international databases. As such, simple ACO definitions will be used to ensure they can be operationalized across a number of databases. As each database used will be specific to a patient population and (in most cases) to one country of origin, use of multiple databases affords a unique opportunity to examine the sensitivity of findings to how populations were included in different databases.Future phases of the REG ACO Working Group’s research programme will go on to characterize the different ACO populations from a clinical perspective (cross sectionally and historically) and to explore potential differential treatment outcomes associated with the different definitions.It is expected to be considerable variation in characterization approaches in the follow-on clinical characterisation and outcome evaluation phases (owing to differences in available variables and the requirement to use a range of proxy measures in order to optimise approaches within each database). As such, this work will be treated as a separate second study phase
• Study status:
  Finalised

Research institutions and networks

Institutions

Observational & Pragmatic Research Institute Pte (OPRI)

United Kingdom

University of Groningen Netherlands, University Hospital Vall d'Hebron Spain, Adelphi Real World UK, Primary Care Majorca Department Spain, OPCRD UK

Networks

Respiratory Effectiveness Group (REG)

Belgium

Denmark

France

Germany

Greece

Hungary

Italy

Netherlands

Spain

Sweden

United Kingdom

Study timelines

Date when funding contract was signed

Planned:31/08/2016

Actual:31/08/2016

Study start date

Planned:31/10/2016

Actual:31/10/2016

Date of final study report

Planned:31/08/2017

Actual:31/08/2018

Sources of funding

Other

More details on funding

Respiratory Effectiveness Group

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable