German Dementia Registry (DEMREG)

Study summary

No information provided.

Study identification

• EU PAS number:
  EUPAS1000000913
• Study ID:
  1000000913
• Official title and acronym:
  German Dementia Registry (DEMREG)
• DARWIN EU® study:
  Yes
• Study countries:
  Germany
• Study description:
  The aim of the German Dementia Registry is to prospectively collect longitudinal real-world data on all consenting patients diagnosed in clinical routine with SCD, MCI, and early dementia of different etiologies in Germany, independent of their actual treatment regimen. For this purpose, an online platform will be provided. ; Data are collected during patient visits and items for data collection are aligned with diagnostic/treatment guidelines and clinical procedures. The disease specific registry will be conducted to prospectively follow the natural course of dementia and to differentiate e.g. patients with Alzheimer’s dementia from patients with dementia of other etiology. ; The data collected will provide prospective and longitudinal data demonstrating the natural course of disease and the current diagnostic and treatment behavior in clinical routine in the German healthcare system. Prospective monitoring of dementia patients is expected to lead to a better understanding of the natural history of dementia and the changes in biomarker values within different etiologies of dementia. This can help to improve and adapt the early diagnostic criteria regarding biomarkers and real-world data for patients on newly approved treatments (e.g. amyloid antibodies).
• Study status:
  Ongoing

Research institutions and networks

Institutions

Uniklinik RWTH Aachen: University Hospital Aachen, Department of Neurology

University Hospital Magdeburg (OVGU)

Germany

Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE)

Germany

1. Department of Neurology, University Hospital Ulm, Germany
2. Department of Neurology, University Hospital Bremen-Ost, Germany
3. Department of Neurology and Policlinic, University Hospital Heidelberg, Germany
4. Psychiatric and Psychotherapeutic Clinic, University Hospital Erlangen, Germany
5. Clinic for Geriatrics, University Medical Center Göttingen, Germany
6. Department of Neurology, University Hospital Essen, Germany
7. Psychiatry and Psychotherapy, University Hospital Tübingen, Germany
8. Center for Mental Health, Immanuel Hospital Rüdersdorf, Brandenburg Medical School Theodor Fontane, Germany
9. Psychiatric and Psychotherapeutic Clinic, Hospital Frankfurt (Oder), Germany
10. Department of Neurology, University of Leipzig Medical Center, Germany
11. Psychiatric and Psychotherapeutic Clinic, Charité University Medicine Berlin, Germany
12. Clinic and Polyclinic for Neurology, University Hospital Hamburg Eppendorf, Germany
13. Clinic for Geriatric Psychiatry, Psychosomatics and Psychotherapy, Pfalzklinikum Klingenmünster, Germany
14. Clinic for Neurology Campus Kiel, University Hospital Schleswig-Holstein, Germany
15. University Hospital Magdeburg, Germany
16. Central Institute for Mental Health, Clinic for Geriatric Psychiatry, Mannheim, Germany
17. Clinic for Psychiatry and Psychotherapy, Homburg, Germany
18. Memory Clinic, Clinic for Gerontopsychiatry, Asklepios Klinik Nord, Ochsenzoll, Germany
19. Clinic for Psychiatry and Psychotherapy, Charité University Medicine Berlin, Germany
20. Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
21. Department of Neurology, Technical University of Munich, School of Medicine and Health, TUM University Hospital, Munich, Germany
22. University Medical Centre of Johannes Gutenberg University Mainz, Department of Psychiatry and Psychotherapy, Mainz, Germany
23. Augsburg University Hospital, Department of Neurology, Augsburg, Germany
24. University Hospital Jena, Department of Neurology, Jena, Germany
25. German Center for Neurodegenerative Diseases (DZNE), Greifswald, Germany
26. Martin-Luther-University Halle-Wittenberg, Department of Neurology, Halle (Saale), Germany

Networks

German Network of Memory Clinics (Deutsches Netzwerk Gedächtnisambulanzen; DNG)

Study timelines

Date when funding contract was signed

Actual:23/02/2021

Study start date

Actual:16/05/2022

Date of final study report

Planned:01/01/2050

Sources of funding

Pharmaceutical company and other private sector 

More details on funding

DEMREG was funded by Biogen (2021–2022) and is currently supported by Eisai (since 2022) and Lilly (since 2023), as well as private donations.

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable

Other study registration identification numbers and links

DRKS00027547 - 01.04.2022

https://drks.de/search/en/trial/DRKS00027547