Prospective intervention study to determine the anesthesia workplace exposure to sevoflurane when using activated carbon filters vs. anesthesia gas scavenging systems. CONTRAGASS

Study identification

• EU PAS number:
  EUPAS1000000807
• Study ID:
  1000000807
• Official title and acronym:
  Prospective intervention study to determine the anesthesia workplace exposure to sevoflurane when using activated carbon filters vs. anesthesia gas scavenging systems. CONTRAGASS
• DARWIN EU® study:
  No
• Study countries:
  Germany
• Study description:
  Small amounts of anesthetic gas inevitably escape during anesthesia due to device-specific leaks and the gas's high volatility. The plan is to compare workplace exposure to anesthetic gases in the operating room using an anesthetic gas scavenging system versus anesthetic gas absorber. ; For this purpose, an automated measuring device will be operated in an operating room. The two methods will be connected prospectively and randomly to the standard ventilator (PRIMUS, Dräger). ; The goal is to compare the minimum residual gas concentration of sevoflurane in the room air per minute of anesthesia as an indicator of workplace exposure.
• Study status:
  Ongoing

Research institutions and networks

Institutions

Hannover Medical School (MHH)

Study timelines

Date when funding contract was signed

Planned:27/10/2025

Actual:27/10/2025

Study start date

Planned:02/11/2025

Actual:02/11/2025

Data analysis start date

Planned:21/12/2025

Date of final study report

Planned:02/05/2026

Sources of funding

No external funding

Regulatory

• Was the study required by a regulatory body?:
  No
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable