Protocol (Pangea ID 2024-14140) Development of Algorithms to Identify Intracerebral Hemorrhage Greater Than 1 cm and Amyloid-Related Imaging Abnormalities Using Electronic Medical Records in Select Populations of Alzheimer’s Disease and Related Dementias and Mild Cognitive Impairment Patients in the United States

Study identification

• EU PAS number:
  EUPAS1000000501
• Study ID:
  1000000501
• Official title and acronym:
  Protocol (Pangea ID 2024-14140) Development of Algorithms to Identify Intracerebral Hemorrhage Greater Than 1 cm and Amyloid-Related Imaging Abnormalities Using Electronic Medical Records in Select Populations of Alzheimer’s Disease and Related Dementias and Mild Cognitive Impairment Patients in the United States
• DARWIN EU® study:
  No
• Study countries:
  United States
• Study description:
  Develop algorithms to identify intracerebral hemorrhage (ICH) greater than 1 cm and amyloid-related imaging; abnormalities (ARIA) using Natural Language Processing (NLP) of unstructured radiology reports from; Electronic Health Record data among patients with Alzheimer’s disease and mild cognitive impairment. Algorithms will be validated using medical chart review.;
• Study status:
  Planned

Research institutions and networks

Institutions

Eli Lilly and Company

Premier Healthcare Solutions, Inc.

Study timelines

Date when funding contract was signed

Actual:27/09/2024

Study start date

Planned:01/01/2026

Date of final study report

Planned:30/01/2027

Sources of funding

Pharmaceutical company and other private sector 

More details on funding

Eli Lilly & Co.

Regulatory

• Was the study required by a regulatory body?:
  Yes
• Is the study required by a Risk Management Plan (RMP)?:
  Not applicable