Study identification

PURI

https://redirect.ema.europa.eu/resource/1000000094

EU PAS number

EUPAS1000000094

Study ID

1000000094

Official title and acronym

Vaccine Effectiveness, Burden and Impact Studies (VEBIS) - Healthcare worker cohort

DARWIN EU® study

No

Study countries

Croatia
Estonia
Greece
Ireland
Italy
Latvia
Poland
Portugal
Romania
Spain

Study description

Starting December 2021, ECDC-funded Vaccine Effectiveness, Burden and Impact (VEBIS) Framework Contract ECDC/2021/017 included the Lot 2: “Assessment of COVID-19 vaccine effectiveness among healthcare workers”. The VEBIS HCW VE cohort study included until 21 May 2023, 19 sites in 10 countries. Real-world VE studies can also answer questions about effectiveness by age group and risk factors, duration of vaccine protection, effectiveness of different vaccines, and effectiveness of the vaccine against new variants of SARS-CoV-2. The frequent testing independent of symptoms is especially relevant during the Omicron period, which is more associated with less severe or asymptomatic disease.

Study status

Ongoing
Research institutions and networks

Institutions

European Centre for Disease Prevention and Control
EpiConcept
First published:
01/02/2024
Institution

Contact details

Camelia Savulescu

Primary lead investigator
Study timelines

Date when funding contract was signed

Actual:

Study start date

Actual:

Date of final study report

Planned:
Sources of funding
Other

More details on funding

Funding from European Centre for Disease Prevention and Control
Study protocol
Initial protocol

Generic protocol for ECDC studies of COVID-19 vaccine effectiveness against confirmed SARS-CoV-2 using healthcare worker cohorts, version 1.0.pdf

English (1.05 MB - PDF)View document
Updated protocol

Generic protocol for ECDC studies of COVID-19 vaccine effectiveness against confirmed SARS-CoV-2 using healthcare worker cohorts, version 3.0.pdf

English (852.03 KB - PDF)View document
Regulatory

Was the study required by a regulatory body?

No

Is the study required by a Risk Management Plan (RMP)?

Not applicable