Teratology Information Service, Helsinki (TIS Helsinki), HUSLAB

The Teratology Information Service is affiliated to the Poison Information Centre,serving the whole country of Finland. The service counsels health care professionals and pregnant and lactating women about risks related to drug exposure. Pregnancies are followed up prospectively to outcome,and a follow-up questionnaire is sent to the mOther/ health care provider after delivery. Data collected at the time of call include maternal characteristics (age,drug exposure,use of tobacco and alcohol and illicit drugs,BMI,chronic diseases,obstetric history and use of folic acid). The follow-up data include pregnancy data,pregnancy outcome data,and infant data (gestational age,birth weight,Apgar score,peri- and neonatal problems,malformations etc). In all pregnancies with first trimester exposure,and those with exposure to new drugs even in later stages of pregnancy,permission for follow-up is requested.