Netherlands Pharmacovigilance Centre Lareb

The Netherlands Pharmacovigilance Centre Lareb collects and analyses reports of suspected adverse drug reactions reported by health care professionals,patients and market authorisation holders in the Netherlands. Lareb informs both government and health professionals about important new signals. The Lareb database presently contains over 100.000 reports. Reports are reviewed on a case-by-case basis. Potential signals undergo further analysis. Statistical techniques are used to support the signal detection process. In addition Lareb gathers information of adverse drug reactions by means of an intensive monitoring system. In his system patients are included when they collect the drug under investigation in the pharmacy for the first time. After on-line registration,the patient will receive questionnaires via e-mail at specific points in time asking for experiences with the drug,including adverse drug reactions (ADRs) and Other information related to drug use.